糖化血红蛋白在妊娠期糖尿病筛查中的应用探讨

Investigation of HbAlc in screeningance gestational diabetesmellitus

目的探讨糖化血红蛋白在妊娠期糖尿病(GDM)筛查中应用价值。方法健康对照组98例、正常妊娠组116例及妊娠糖尿病组82进行了空腹血糖、口服75g葡萄糖筛查试验、糖化血红蛋白测定。结果健康对照组与正常妊娠组比较,FPG及HbAlc无差异(P>0.05),GDM组妊娠中期HbAlc水平高于正常妊娠组及健康对照组,差异有统计学意义,P<0.01。结论 HbAlc筛查在妊娠糖尿病诊断和监测中具有一定价值。

Objective To evaluate the application probability of Glycosylated hemoglobine A1c in the inscreening gestational mllitus（GDM）.Methods The fasting blood glucose（FPG）,taking 75g glucose Screening test（OGTT） and glycosylated hemoglobin（HBA1c）：116 normal pregnancy,82 fasting glucose（FPG）,98 healthy controls were carried out.Results The results shows that there were no significant different in FPG,OGTT and HbA1c beteen the nomal pregnancy and the healthy controls（P0.05）.The serum levels of FPG,OGTT and HbA1c in gestational diabetes were significanthy higher than those in normal pregnancy and healthy controls（P0.01）.Conclusions HbA1c plays an important role in the inscreening gestational mllitus（GDM）.