普米克气雾剂干预婴幼儿喘息反复发作疗效观察

Effect of Pulmicort aerosol on infants with wheezing disorders

目的观察普米克气雾剂干预能否减少婴幼儿喘息性疾病的反复发作。方法选择2008年6月—2009年5月,首次发作的婴幼儿喘息性疾病60例,随机分为治疗组(30例)和对照组(30例)。治疗组,在急性喘息控制后给予普米克气雾剂吸入干预治疗70d,并观察治疗结束后1年患儿反复喘息发生的情况。对照组未给予治疗。结果在1年随访中,治疗组喘息复发5例,共13人次,平均1年发作0.43次;对照组喘息复发17例,共76人次,平均1年发作2.53次。治疗组复发次数明显减少,两组比较差异有统计学意义(P<0.05)。结论普米剂克气雾剂干预可以减少1年内婴幼儿喘息性疾病的发作次数,简单实用,值得推广。

Objective To observe whether using Pulmicort aerosol on infants with wheezing disorders can reduce the recurrence of those infants＇ or not.Methods We choosed 60 infants with wheezing disorders for the first episode from June 2008 to May 2009.They were randomly divided into two groups： treatment group（30 cases） and control group（30 cases）.Treatment group： Pulmicort aerosol were used for 70 days after controlling patients＇ acute wheezing;We observed the recurrence of wheezing disorders in one year after the treatment.Control group were not given treatment.Results In the one year follow-up,5 cases in treatment group had recurrence,a total of 13 times,on average 0.43 per one year.17 cases in control group had recurrence,a total of 76 times,on average 2.53 per one year.Recurrence of patients in treatment group was significantly reduced.Difference between two groups was statistically significant（P0.05）. Conclusions Using Pulmicort aerosol on infants with wheezing disorders can reduce the recurrence in one year.It is simple and practical,so it worth promoting.