阿奇霉素辅助治疗小儿咳嗽变异性哮喘疗效观察

Observation of effect of Azithromycin in treatment of cough variant asthma

目的探讨阿奇霉素在治疗小儿咳嗽变异性哮喘中的临床疗效。方法将196例咳嗽变异性哮喘患儿随机分为对照组和治疗组,每组各98例。对照组常规给予扩张支气管药物综合治疗,治疗组加用阿奇霉素治疗。结果治疗组和对照组总有效率分别是93.9%和71.4%。经统计学处理两组有极显著性差异(P<0.05)。未发现明显不良反应。结论阿奇霉素治疗小儿咳嗽变异性哮喘疗效显著。

Objective To study the clinical efficacy of Azithromycin in treatment of cough variant asthma in children.Methods Totally 196 cases of cough variant asthma of children were randomly divided into controll and treatrnent group.98 cases of controlled group were regularly treated with common bronchodilators.But 98 cases of treatrnent group were added with Azithromycin.Results The overall effective rate of treatrnent group was remarkably higher than that of controlled group（93.9% VS 71.4%）（P0.05）.And no side effect could be found in all of the treated children.ConclusionsAzithromycin can be used in treating the children with cough variant asthma and improving the clinical symptoms with high safety.