注射用美罗培南治疗小儿ESBLs阳性大肠埃希菌肺炎疗效观察

Effect observation of meropenem injection in treatment of ESBLs positive escherichia coli pneumonia in children

目的探讨注射用美罗培南治疗小儿ESBLs阳性大肠埃希菌肺炎疗效。方法选取从2007年1月至2010年6月在我院住院的ESBLs阳性大肠埃希菌肺炎54例,随机分为2组,每组27例,对照组在常规治疗的基础上应用注射用头孢吡肟,治疗组在常规治疗的基础上采用注射用美罗培南。结果注射用美罗培南可显著缓解ESBLs阳性大肠埃希菌肺炎的临床症状,总有效率显著高于对照组(P<0.05),其差异具有统计学意义。结论注射用美罗培南治疗产ESBLs大肠埃希菌肺炎疗效显著。

Objective To investigate the effect of meropenem injection in treatment of ESBLs positive escherichia coli pneumonia in children.Methods We selected from January 2007 to June 2010 of 54 cases of ESBLs positive escherichia coli pneumonia in our hospital,were randomly divided into two groups each 27 cases,patients in the control group were based on the application of conventional therapy with cefepime injection,the treatment group with conventional therapy on the basis of application of meropenem injection.Results Meropenem injection can significantly ease the ESBLs-positive escherichia coli pneumonia,the total effective rate was significantly higher（P0.05）,the difference was statistically significant.Conclusions The effect of Meropenem injection in treatment of ESBLs positive escherichia coli pneumonia is significant.