摘要
以对苯二甲酸二甲酯和2,5-二氯苯胺为原料,经溶剂硝化、水解、酰氯化、缩合、还原合成了2-氨基-4-((2,5-二氯苯基)氨甲酰基)苯甲酸甲酯(MMTDCA),反应总收率达65%。考察了不同催化剂、溶剂、反应温度、摩尔比等对反应的影响。目标产物结构经IR、1H-NMR表征。
The methyl 2-amino-4-（（2,5-dichlorophenyl）carbamoyl）benzoate（MMTDCA）was synthesized from dimethyl terephthalate and 2,5-dichloroaniline by nitration,hydrolyzation,acyl chlorination,condensation and reduction.The total yield of the title compound was more than 65%. The effects of catalysts,solvents,reaction temperature and ratio of reactants on the reaction were investigated and the structure of the product was characterized by IR and 1H-NMR spectra.
出处
《染料与染色》
CAS
2011年第4期41-42,共2页
Dyestuffs and Coloration
基金
杭州市属高校绿色精细化工研究与技术转化重点实验室开放基金项目(KFJ201004)
