期刊文献+

基于动物模型研究的气体实验系统的设计 被引量:1

Design of gas experimental system based on the animal model study
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摘要 针对环境中SO2浓度与哮喘发病关系的动物模型研究,设计了可以模拟含有特定SO2浓度的气体环境的实验系统。通过以单片机C8051F310为核心,构建了气路流体系统、传感检测系统和智能控制系统,实现了SO2浓度在密闭环境中的智能化控制。实验系统能够模拟SO2浓度为0~28.56μg/L的大气环境,在长期的实验中表现出良好SO2浓度控制效果。该系统是一种操作简便、可靠性高的SO2气体实验系统,为SO2哮喘动物模型研究提供了适宜的必备工程系统。 To supply a technical way of studying the relation between asthma and the density of SO2 in environment, an air experimental system is developed for simulating the special environment with SO2. Airsupplying subsystem, detecting subsystem with sensors and intelligent controlling subsystem are designed, and intelligent control on special SO2 density in a seal box is realized, based on the MCU of C8051F310. The system can simulate a special environment with the SO2 density of 0 ~28.56 μg/L and show great effect in experiments. The system is easy to operate and has high reliability, and is a suitable technical tool for studying the relation between asthma and SO2.
出处 《传感器与微系统》 CSCD 北大核心 2011年第9期125-127,共3页 Transducer and Microsystem Technologies
基金 国家自然科学基金资助项目(30770529) 重庆市自然科学基金重点资助项目(CSTC 2010BA5001) 重庆大学大型仪器设备开放基金资助项目(2010063057)
关键词 哮喘 SO2 动物模型 智能控制 大气模拟 asthma SO2 animal model intelligence control atmospheric simulation
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参考文献11

  • 1Global Initiative for Asthma (GINA). Pocket guide for asthma management and prevention( updated 2009 ) : Global strategy for asthma management and prevention [ EB/OL ]. [ 2010-07-26 ]. http ://www. ginasthma, org.
  • 2National Asthma Education and Prevention Program. Expert Panel Report 3 ( EPR -3 ) .: Guidelines for the Diagnosis and Management of Asthma Summary Report 2007 [J]. Allergy Clin Immunol,2007,120 : 94 -138.
  • 3Global Initiative for Asthma( GINA). The global burden of asthma ( updated 2009 ) [EB/OL]. [ 2010-07-261. http://www. ginas-thma. org.
  • 4田文华,彭希哲,梁鸿.城市空气污染造成儿童健康经济损失的研究[J].中国卫生经济,2002,21(10):16-17. 被引量:7
  • 5Garry B Z, Kosman E, Ganor E, et al. Emergency room visits of asthmatic children, relation to air pollution, weather, and airborne allergens [ J ]. Ann Allergy Asthma Immunol, 1998,81 (6) : 563 -570.
  • 6Hajat S, Haines A, Goubet S A, et al. Association of air pollution with daily GP consultations for asthma and other lower respiratory conditions in London [J]. Thorax , 1999,54 ( 7 ) :597 -605.
  • 7李洁.香港医学界认为哮喘同三种空气污染物有关[J].医学信息,1997,0(1):7-7. 被引量:1
  • 8Samukawa T, Arasidani K. C-jun mRNA expression and profilin mRNA amplification in rat alveolar macrophages exposed to volcanic ash and sulfur dioxide [ J ]. Ind Health, 2003, 41 ( 4 ) : 313 -319.
  • 9Horstman D H, Folinsbee L J. Sulfur dioxide-induced bronchoconstriction in asthmatics exposed for short durations under controlled conditions : A selected review [C]//Susceptibility to In- haled Pollutants, ASTM STP 1024, Philadelphia, 1989:195 - 206.
  • 10潘琢金.C8051F310/1混合信号ISPFLASH微控制数据手册[Z/OL].[2010-07-26].http://www.hqdz.com/C8051F/C8051F31x.pdf.

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  • 1周俊波,刘洋.Fluent6.3流场分析从入门到精通[M].北京:机械工业出版社,2012.
  • 2Harting JM, Roy CJ. The automated bioaerosol exposure system: preclinical platform development and a respiratory dosimetry ap- plication with nonhuman primates [ J ]. J Pharmacol Toxicol Methods,2004, 49( 1 ) :39 -55.
  • 3Smallshaw JE, Richardson JA, Vitetta ES. RiVax, a recombi- nant ricin subunit vaccine, protects mice against ricin delivered by garage or aerosol[ J ]. Vaccine, 2(107, 25(42 ) :7459 - 7469.
  • 4Chen WX, Lee RK, Shen H, et al. Susceptibility of immunode- ficient mice to aerosol and systemic infection with virulent strains of Frarwisella tulareris [ J]. Microb Pathogen, 2004, 36 ( 6 ) : 311 -318.
  • 5Shen H, Chen WX, Conlan JW. Susceptibility of various mouse strains to systemically or aerosol-initiated tularemia by virulent type A Francisella tularensis before and after immunization with the attenuated live vaccine strain of the pathogen [ J ]. Vaccine, 2004, 22( 17 - 18) :2116 -2121.
  • 6张洪良,孙付伟,王发辉.基于FLUENT的手术室流场分析研究[J].河南理工大学学报(自然科学版),2008,27(5):520-523. 被引量:1
  • 7孙磊,安辉,郑有科,曹佳.模拟密闭舱室烟雾吸入染毒装置的研制[J].第三军医大学学报,2009,31(4):290-293. 被引量:8
  • 8徐建,陆宇,郑梅琴,付雷,赵伟杰,王彬,李芃.气溶胶感染小鼠急性结核病模型的建立及应用[J].中国防痨杂志,2010,32(8):462-465. 被引量:6
  • 9魏兰芬,张磊,许激,潘协商,朱一凡,林军明.生物气溶胶粒径分布及稳定性研究[J].中国消毒学杂志,2011,28(2):158-160. 被引量:11
  • 10李娜,温占波,杨文慧,王洁,李劲松,胡凌飞,董晓凯,刘克洋,曹杰.一种正压生物防护服细菌气溶胶防护效果的研究[J].军事医学,2011,35(8):566-569. 被引量:5

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