摘要
目的研究脂联素与2型糖尿病合并冠心病相关性,探讨脂联素与2型糖尿病合并冠心病的作用和机制。方法选择正常对照组48例、2型糖尿病组62例和2型糖尿病合并冠心病组68例,测定脂联素、糖化血红蛋白、总胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白、空腹血糖、空腹胰岛素进行观察。结果脂联素、胰岛素抵抗指数存在负相关关系,脂联素与性别、GHbAlc、FINS、BMI、LDL、TG独立相关。结论脂联素水平的降低与2型糖尿病合并冠心病形成有关。
Objective To investigate the association of adiponectin with Type 2 Diabetes Mellitus with Coronary Heart Disease. Methods The adiponectin, GHbAlc, TC, TG, HDL, LDL, FPG and FINS were measured in 45 healthy people, 55 patients with T2DM, and 60 patients with T2DM with Coronary Heart Disease. Results The adiponectin showed association with sex, GHbAlc, FINS, BMI, LDL and TG, and negative association with HOMA - IR. Conclusion The decrease of adiponectin was related to the occurrence and development of cardiovascular complication of patients of T2DM.
出处
《中国医学创新》
CAS
2011年第25期5-8,共4页
Medical Innovation of China
关键词
脂联素
2型糖尿病
冠心病
Adiponectin
T2DM
Coronary Heart Disease
