沈阳地区0～16岁血清碱性磷酸酶参考值的探讨

Study on the reference value of serum alkaline phosphatase of 0～16 years old in Shenyang area

【目的】探讨沈阳地区0～16岁未成年人血清碱性磷酸酶(alkaline phosphatase,ALP)的参考值范围。【方法】应用SPSS 17.0软件对1 447例16岁以下健康未成年体检者血清ALP水平进行分组分析,从而得到沈阳地区不同年龄段血清ALP的参考值范围。【结果】建立沈阳地区16岁以下未成年人血清ALP的参考值范围。所有16岁以下未成年人的血清ALP均值明显高于成年人。男性和女性血清ALP均值比较,6岁以下组差异无统计学意义(P>0.05),而6岁以上组差异有统计学意义(P<0.05)。男性和女性的血清ALP均值有两次交叉,总体趋势是出生后血清ALP均值水平较高,随后轻度下降,3岁以后又缓慢上升,青春期前后显著下降。【结论】应该建立各年龄段未成年人血清ALP的参考值范围,以此来正确评价未成年人的生长发育状况。

[Objective] To study the reference value of serum alkaline phosphatase（ALP） on minor aged 0-16 years old in Shenyang area. [Methods] Applying SPSS 17.0, ALP of 1 447 minor under 16 years old were analyzed by grouping, The reference value of minor serum ALP was set up by statistic methods. [Results] The reference value of minor serum ALP under 16 years old was set up. ALP of minor were higher than those of adult. The difference of ALP between male and female above 6 years old were significant, but were not under 6 years old. The ALP between male and female were superposed twice. The collectivity tendency were those ALP were higher in newborn and above 3 years old, but were de clined under 3 years old and adolescence. [Conclusion] It is essential to set up the reference value of minor serum ALP.