我院209例药品不良反应报告分析

Analysis on 209 Cases of ADR Reports in Our Hospital

目的分析医院药品不良反应(ADR)的发生情况,促进临床合理用药。方法采用回顾性研究方法,对209份药品不良反应报告中患者年龄、性别、涉及药品种类、给药途径、临床表现等进行统计分析。结果抗感染药物引起的药品不良反应占73.21%,其次为中药制剂,占10%。给药途径以静脉滴注为主,占78.95%;药品不良反应主要临床表现为皮肤损害,占54.01%。结论临床用药应合理控制抗感染药物的使用,慎用中药制剂,并加强药品不良反应监测工作,以减少不良反应的发生。

Objective To analyze the status of adverse drug reactions（ADR） in our hospital in order to promote rational drug use in clinic.Methods By the retrospective study,209 cases of ADR report in our hospital were collected and analyzed in aspects of age and sex,drug varieties,route of administration and clinical manifestation.Results Of all the ADR cases reported in our hospital,73.21%were induced by anti-infective drugs,10%by traditional Chinese medicines.78.95%were caused by intravenous drip.The main manifestations of ADR were skin lesions（54.01%）.Conclusion The use of anti-infective drugs should be rationally controlled in clinical medication.The traditional Chinese medicines should be used cautiously.Furthermore,monitoring of ADR should be strengthened to reduce the occurrence of ADR.