肠道天然免疫抗艾滋病病毒作用及中医药干预研究概述

Natural immunity of the intestinal mucosa induced by Chinese medicine can reduce HIV

天然免疫系统是机体抵御外来病原体的第一道防线,在此基础上衍生出十分复杂的获得性免疫反应。肠黏膜系统是HIV复制的重要贮存库,通过艾滋病肠道症状机制的研究,发现在HIV的感染致病过程中,肠道黏膜先天免疫发挥着重要的作用。长期的临床和实验研究发现中医药能够改善肠道黏膜天然免疫功能。因此提出应用中医药诱导肠黏膜天然免疫可能有助于清除病毒,从而降低血浆病毒负荷。

Innate immune system is the first line of defense of the body against foreign pathogens,which gives birth to a very complex acquired immune response.Intestinal mucosa system is an important repository for HIV replication.By studying the mechanisms of intestinal symptoms of AIDS,we found that the innate immunity of the intestinal mucosa played an important role during the process of HIV infection.It was also found that Chinese medicine could improve the innate immunity of intestinal mucosa during our long-term clinical and experimental studies.Therefore,it is proposed that natural immunity of the intestinal mucosa induced by Chinese medicine can effectively remove the repository,thereby reducing the plasma viral load.