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非诺贝特对肾移植术后高脂血症的疗效观察

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摘要 目的:观察非诺贝特对肾移植术后高脂血症的疗效。方法:选择本院2009年9月~2010年6月32例肾移植术后并发高血脂患者,给予口服非诺贝特胶囊,于服药前、服药4周取清晨空腹血测定血浆血脂水平进行比较。结果:治疗4周后,32例高脂血症患者血脂水平均有不同程度的改善,三酰甘油(TG)、胆固醇(TC)及低密度脂蛋白胆固醇(LDL-C)显著下降,高密度脂蛋白胆固醇(HDL-C)显著上升,其中以TG下降最为明显。结论:高脂血症是肾脏移植术后应用免疫抑制剂的常见并发症,非诺贝特对免疫抑制剂药效影响小,能够显著改善高脂血症,是一种安全有效的血脂调节药物。
出处 《中国当代医药》 2011年第10期60-60,64,共2页 China Modern Medicine
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参考文献5

  • 1Manu M,Tanabe K.Impaet of tacrolimus on hyper-lipidemia after renal transplantation:a Japanese single center experience[J].Transplantation Proceedings,2000,32:1736-1738.
  • 2舒春兰,周临生,雷小勇,成元桂.氟伐他汀对高脂血症患者的血脂及细胞粘附分子的影响[J].中国动脉硬化杂志,2002,10(1):62-64. 被引量:25
  • 3Massy ZA.Hyperlipidemia and cardiovascular disease after organ transpltanation[J].Transplantation,2001,72(6 Suppl):13-15.
  • 4AkiokaK,Takahara S,lehikawa S,et al.Faetors Predicting Long-term Graft Survival after Kidney Transplantation:Multieenter Study in Japan[J].World J Surg,2005,29(2):249-256.
  • 5Aakhus S,Dahlk-wideroe TE.Hyperlipidaemia in renal transplantation patients[J].J hat Med,1996,239:407-415.

二级参考文献7

  • 1Hillis GS, Flapan AD. Cell adhesion molecules in cardiovascular disease:a clinical perspective. Heart, 1998, 79(5): 429-431
  • 2Inuzuka H, Seita T, Okamotto K, et al. A sensitive ELISA for the characterization of two forms of circulating intercellular adhesion molecule 1 in human plasma. Bull, 1995, 18: 1 036
  • 3Malini Haria, Donna Mc Tavish. Pravastatin: a reappraisal of its pharmacological properties and clinical effectiveness in the management of coronary heart disease. Drugs, 1997, 53 (2): 299
  • 4Filippo C, Luigi MB, Antonion B, et al. Role of inflammation in the pathogenesis of unstable coronary artery disease. Am J Cardiol, 1997, 80 (5A): 10-16
  • 5Hackman A, Abe Y, Insull W Jr, et al. Levels of soluble cell adhesion molecules in patients with dyslipidemia. Circulation, 1996, 93: 1 334
  • 6Cominacini L, Garbin U, Pasini AF, et al. Antioxidants inhibit the exprssion of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 induced by oxidized LDL on human umbilical vein endothelial cells. Free Radic Biol Med, 1997, 22: 117
  • 7陈晖,沈潞华,谢苗荣,李东宝.氟伐他汀对内膜损伤后动脉粥样硬化家兔内皮功能的改善作用[J].中国动脉硬化杂志,2000,8(1):39-42. 被引量:11

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