泌尿生殖道支原体感染状况及耐药性分析

目的:以本地区为例,不同性别、年龄患者标本中支原体感染率及支原体对抗生素的耐药性。方法:采用珠海丽珠试剂股份有限公司生产的解脲脲原体和人型支原体分离鉴定、药敏试剂盒进行检测和药敏试验。结果:本地区680例标本支原体的总检出率为46.5%,男性检出率为26.9%,女性检出率为51.1%,高发年龄阶段为20～30岁和大于40岁;316例阳性中Uu阳性240例,占75.9%;Uu感染敏感率在80%以上的为克拉霉素、美满霉素、强力霉素、交沙霉素;Mh感染敏感率在90%以上的为强力霉素、美满霉素、交沙霉素;Uu和Mh合并感染敏感率在80%以上的为美满霉素、强力霉素、交沙霉素。结论:本地区支原体感染以女性为主,高发年龄为20～30岁和大于40岁,且以单纯Uu感染为主,治疗首选美满霉素、强力霉素、交沙霉素。

Objective To investigate the infection status and drug resistance of genitourinary tract mycoplasma in Hanzhong city,Shan’xi proivince and Method The mycoplasma culture and drug sensitivity test were done using Zhuhai Yinke kits.Results 46.5%（316 out of 680） individuals were found infected by mycoplasma,75.5% was ureaplasma urealyticum（Uu）.26.9% males were infected by mycoplasma,while 51.1% females were found mycoplasma positive.Individuals aged from 20 to 30 years or 40 years are easily to be infected.The drug resistance rate of Uu to Clarithromycin、Minocycline、Doxycycline、and Josamycin was less than 20%;the resistance rate of Mh to Doxycycline、Minocycline、and Josamycin was 10%;the resistance rate of co-infec-tion of Mh and Uu to Minocycline、Doxycycline、Josamycin was 20%.Conclusion Females in our district were more susceptible to mycoplasma,and were mainly infected by Uu alone,especially individuals aged from 20 to 30 years or 40 years.Minocycline、 Doxycycline、and Josamycin were best choice.