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中西医结合治疗奥沙利铂致神经毒性24例 被引量:3

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摘要 目的:观察中西医结合治疗奥沙利铂致神经毒性的临床疗效。方法:将46例患者随机分为对照组22例和治疗组24例,对照组给予甲钴铵片治疗,治疗组在对照组治疗的基础上加用自拟健脾温经方治疗,30 d为1疗程,1疗程后观察疗效。结果:对照组22例,显效4例,有效6例,无效12例,有效率为45.5%;治疗组24例,显效8例,有效10例,无效6例,有效率为75.0%。结论:中西医结合治疗奥沙利铂致神经毒性疗效满意。
作者 陈清华
出处 《河南中医》 2011年第9期1034-1034,共1页 Henan Traditional Chinese Medicine
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  • 1胡发明.奥沙利铂的不良反应和安全性[J].国外医药合成药·生化药·制剂分册,1999,20(3):184-185.
  • 2周际昌.实用中瘤内科学[M](第2版)[M].北京:人民卫生出版社,2003,4..
  • 3Levi F, Misset JL, Brienza S, et al. A chronopharmacologic phase Ⅱ clinical trial with 5-fluorouracil, folinic acid, and oxaliplatin using an ambulatory multichannel programmable pump. Highantitumor effectiveness against metastatic colorectal cancer[J]. Cancer,1992,69(4):893-900.
  • 4Misset JL.Oxaliplatin in practice .Br J Cancer ,1998,77(Suppl 4)∶S4-S7.
  • 5Grothey A, Schmoll HJ. New chemotherapy approaches in colorectal cancer[J]. Curt Opin Oncol,2001,13(4) :275-286.
  • 6Beeouam Y, Agostini C, Trufflandier N, et al. Oradiplatin : Available data in non-colorectal gastrointestinal malignancies[J]. Crit Rev Oncol Hematol, 2001,40(3):265-272.
  • 7Cassidy J, Misaet JL. Oxalipatin-related side effects: Characteris ticsand management[J]. Semin 0neol,2002,29[5 Suppl 15] : 11-20.
  • 8Wilson RH,Lehky T,Thomas RR, et al. Acute oxaliplatin-induced peripheral nerve hyperexcitability[J].J Clin Oncol, 2002,20 (7):1767-1774.
  • 9Adelsherger H, Quasthoff S, Groeskreutz J, at al. The chemotherapeutic oxaliplatin alters voltage-gated Na^+ channel kinetics on rat sensory neurons[J] .Eur J Pharmacol,2000,406(1) :25-32.
  • 10Maindrault- Gocbel F, Toumigand C, Andre T, et al. Oxaliplatin reintroduction in patients previously treated with leucovorin, fluorouracil and oxaliplatin for metastatic colorectal cancer[J]. Ann Oncol, 2004, 15(8) : 1210-1214.

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  • 1弓晓霞.补阳还五汤预防奥沙利铂外周神经毒性的临床观察[J].河南中医,2005,25(11):68-68. 被引量:24
  • 2李倩,郭伟剑,郑磊贞.奥沙利铂的神经毒性和防治进展[J].上海交通大学学报(医学版),2006,26(4):430-433. 被引量:50
  • 3李明颖,徐建明,宋三泰.奥沙利铂的神经毒性机理与防治方法研究进展[J].中华医学杂志,2006,86(19):1365-1367. 被引量:40
  • 4董雪,李平.奥沙利铂神经毒性机制和预防研究进展[J].中国临床保健杂志,2007,10(2):215-218. 被引量:9
  • 5Wilson RH,Lehky T,Thomas RR,et al.Acute Oxaliplatin Induced Peripheral Nerve Hyperexcitability[J].J Clin Oncol,2002,20(7):1767-1774.
  • 6Kelly H,Goldberg RM.Systemic therapy formetastatic colorectal cancer:current options,current evidence[J].J Clin Oncol,2005,23(20):4553-4560.
  • 7Andre T,Boni C,Mounedji-Boudiaf L,et al.Oxaliplatin,fluorouracil,and leucovorin as adjuvant treatment for colon cancer[J].N Engl J Med,2004,350:2343-2351.
  • 8Levi F,Misset JL,Brienza S,et al.A chronopharmacologic phase II clinical trial with 5-fluorouracil,folinic acid,and oxaliplatin using an ambulatory multichannel programmable pump.High antitumor effectiveness against metastatic colorectal cancer[J].Cancer,1992,69(4):893-900.
  • 9Miller AB,Hoogstraten B,Staquest M,et al.Reporting results of cancer treatment[J].Cancer 47:207-214,1981.
  • 10Cancer Therapy Evaluation Program,Common Terminology Criteria for Adverse Events,Version 3.0,National Cancer Institute online,2006-08-09,cited 2007-07-01;2(1):73 screens.Available from URL:http://ctep.cancer.gov/protocol Development/electronic_applications/docs/ctcaev3.pdf.

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