He-Ne激光与扩束CO_2激光照射对骨折愈合的影响

Effect of He-Ne Laser and CO_2 Laser on Bone Fracture Healing

目的比较相同剂量的He-Ne激光与CO2激光照射对骨折的疗效。方法 36只健康雄性兔制成骨折模型,随机分为三组,每组12只。He-Ne激光组:He-Ne激光扩束照射骨折区;CO2激光组:CO2激光扩束照射骨折组;对照组:常规治疗。通过X片,观察骨折愈合情况,测定骨痂中钙和胶原含量及生物力学抗扭性能,比较三组的疗效。结果 (1)骨折愈合效果:两激光组均优于对照组(P<0.05或P<0.01),且治疗后25 d,CO2激光组优于He-Ne激光组(P<0.05)。(2)胶原蛋白、钙含量:两激光组高于对照组(P<0.05),CO2激光组好于He-Ne激光组(P<0.05)。(3)生物力学抗扭强度:两激光组的最小扭矩(T8°)和瞬间扭矩(Tmax)均高于对照组(P<0.01),CO2激光组Tmax高于He-Ne激光组。结论 He-Ne激光与CO2激光照射对骨折愈合均有促进作用,且CO2激光更好于He-Ne激光。

Objective To observe and compare the discrepancy of curative effect of He-Ne laser and CO2 laser irradiation under the same dosage. Methods The bone fracture pattern was made to 36 healthy male rabbits,who were randomly divided into 3 groups（each 12） ： He-Ne laser group： expanding a bunch of the He-Ne laser project light upon the bone fracture zone,CO2 laser group： expanding a bunch of the CO2 laser irradiation,and matched control group：the routine cures.The different therapy impact was observed on the bone fracture healing.Observed X-ray,detected the contents of collagen and calcium in the callus,and measured the biomechanics anti-torsion strength to evaluate curative effect. Results（1） Fracture healing effect： the two laser groups were better than the control group（P0.05 or 0.01）,and 25 days after treatment,CO2 laser group was better than He-Ne laser group（P0.05）.（2）Collagen and calcium content： two laser groups were higher than control group（P0.05）,and CO2 laser group was better than He-Ne laser group（P0.05）.（3） Biomechanics anti-torsion strength：the minimum torque（T8°） and instantaneous torque（Tmax） of both laser groups were higher than that of control group（P0.01）,and the Tmax of CO2 laser group was higher than that of He-Ne laser group. Conclusions He-Ne laser and CO2 laser irradiation can promote healing of the bone fracture,and the CO2 laser is better.