普通外科肿瘤病人术后手术部位感染的易感因素分析

Risk factors associated with surgical site infection in tumor patients after general surgery

目的:探讨普外肿瘤病人术后手术部位感染(surgical site infection,SSI)的相关易感因素。方法:回顾性分析我院普外科2008年9月-2010年9月实施的638例肿瘤病人手术部位发生感染的情况。结果:638例肿瘤病人,有61例发生SSI,占9.6%。单因素分析显示SSI与手术类别、手术时间、术前预防性应用抗生素、切口类型、术前白蛋白水平、手术方式及ASA分级有明显相关性(P<0.05)。多因素Logistic回归分析显示术前白蛋白水平、切口类型及ASA分级是诱发普外肿瘤病人SSI的独立高危因素(P<0.05)。结论:切口类型、术前白蛋白水平以及ASA分级是SSI的独立危险因素,针对以上高危因素及早采取合理、有效的防治措施是减少普外肿瘤病人SSI的关键。

Objective：To study the risk factors of surgical site infection（SSI） in tumor patients after general surgery.Methods： Six hundred and thirty-eight tumor patients after general surgery were retrospectively studied in the department of hepatobiliary surgery between September 2008 and September 2010.Results： SSI occurred in 61 of 638 tumor patients after general surgery（9.6%）.Univariate analysis showed that types of operation,operation time,prophylactic antibiotics,wound class,preoperative albumin level,surgical approach and ASA grade were significantly associated with SSI（P0.05）.Multivariate analysis showed that preoperative albumin level,wound class and ASA grade were independent risk factors for SSI（P0.05）.Conclusion： Preoperative albumin level,wound class and ASA grade were independent risk factors for SSI.Surveillance for these high risk factors and earlier reasonable treatments are vital to decrease the incidence of SSI in tumor patients after general surgery.