青年人胃癌的临床特征分析

Clinical features of gastric carcinoma in young patients

目的:探讨青年人胃癌的临床症状、病理特征。方法:回顾性分析41例青年人胃癌患者的发病诱因、临床特征和疗效。结果:青年人胃癌女性多发,男女之比为1∶1.56。临床首发症状以上腹部疼痛、上腹部饱胀等为主,幽门螺旋杆菌(Helicobator pylori,Hp)感染率明显高。发病部位以胃窦、胃体为主;病理类型以低分化腺癌、黏液细胞癌及印戒细胞癌为主,生长方式以BorrmannⅢ型、Ⅳ型多见。结论:青年人胃癌恶性程度高,分化低,进展速度快,预后差。早期发现、尽早实施根治手术切除是提高治愈率和生存率的关键。

Objective：To investigate the clinical symptoms and the clinico-pathological characteristics of gastric carcinoma in young patients.Methodes： The predisposing factors,clinical features and therapeutic outcomes in 41 cases of gastric carcinoma in young patients were retrospectively analyzed.Results： Among young patients with gastric carcinoma,there were more female patients,the ratio of male to female was 1∶1.56.There were more cases with epigastrium pain,epigastrium distend as the first occurred clinical manifestation.There were more cases with Helicobacter pylori infection.The tumor sites of origin were mainly located in gastric sinus or gastri body.There were more cases with poorly differentiated,muco-cellular and signet-ring cell adenocarcinoma histologically.The most common gross type was Borrmann type Ⅲ and type IV.Conclusion： Young patients with gastric carcinomas carry worse degree,lower differentiation,faster progress and poorer prognosis.Early identification and radical resection treatment are necessary to improve curative and survival rates in young patients.