弱视眼的视网膜厚度分析

Analysis of the retinal thickness in amblyopia eyes

目的探讨弱视眼是否存在视网膜形态学改变。方法从门诊患儿中搜集弱视眼22例(30只眼)、正常对照眼19例(30只眼),利用相干光断层扫描技术(OCT)对被检眼的黄斑区进行快速扫描,测量黄斑中心凹、中心区(1 mm直径范围)及旁中心区(直径为3 mm环形区域内)四象限的平均视网膜厚度,比较不同区域视网膜厚度之间的差别。结果弱视眼与正常对照眼的黄斑中心凹、中心区视网膜厚度比较,差异有统计学意义。黄斑旁中心区上方、下方、鼻侧及颞侧视网膜厚度,两组差异均无显著性。结论弱视眼黄斑中心凹、中心区视网膜增厚,这种改变可能与弱视的发病机制有关。

Objective To investigate whether the morphology of macula changes or not.Methods To collect 22cases（30 eyes） of amblyopia eyes and 19cases（30eyes） of normal control eyes from out-patient.They were fast-scaned by using OCT in the macula.Average thickness of the foveola 、the fovea and the parafovea was then assessed.Finally,the retinal thickness was compared in different areas.Results There was significant difference in the foveola and fovea thickness between amblyopia eyes and normal control eyes.There was no significant difference in the thickness of superior、 inferior、 nasal、temporal parafovea between them.Conclusion The retinal thicknesses of foveola and fovea in amblyopia eyes was thicker than it in normal control eyes.This change maybe related to the pathogenesis of amblyopia.