非糜烂性反流病患者症状与心理状态相关性分析

Correlation Analysis between States of Mind and Symptoms of Patients with Non-erosive Reflux Disease

目的研究非糜烂性反流病(NERD)患者症状与焦虑、抑郁状态之间的关系。方法对符合NERD诊断标准(2006年三亚共识意见诊断标准)的120例患者进行调查,填写反流性疾病问卷(RDQ)、中医肝胃不和证问卷、焦虑自评量表(SAS)、抑郁自评量表(SDS),分析症状评分与焦虑、抑郁量表评分之间的相关性。结果 NERD患者RDQ症状评分与SAS、SDS评分的相关系数分别为0.262 11、0.305 20(P<0.01),肝胃不和证症状评分与SAS、SDS评分的相关系数分别为0.412 91、0.332 73(P<0.01)。结论 NERD患者反流症状及肝胃不和证症状与焦虑、抑郁状态关系密切,症状的严重程度与心理状态呈正相关,二者互相影响、互为因果。

Objective To study the correlation between symptoms of patients with non-erosive reflux disease （NERD） and depression or anxiety states. Methods One hundred and twenty patients met criterions of NERD were investigated, and filled in Reflux Diagnostic Questionnaires （RDQ）, symptoms scale of in-coordination syndrome of liver and stomach, Self-rating Depression Scale （SDS）, Self-rating Anxiety Scale （SAS）, then the correlations between the states of mind and symptoms of patients were analyzed by the method of linear correlation. Results The correlation coefficient between scores of RDQ of patients and SAS or SDS were 0.262 11 and 0.305 20, respectively （P〈0.01）, and the correlation coefficient （r） between scores of symptoms scale of in-coordination syndrome of liver and stomach and SAS or SDS were 0.412 91 and 0.332 73, respectively （P〈0.01）. Conclusion There were close relationship between the symptoms and depression or anxiety states. The severity of symptoms and states of mind was positively correlated, and both were mutual influence, reciprocal causation.