期刊文献+

肝移植术后中远期并发症及其转归 被引量:1

下载PDF
导出
摘要 目的探讨肝移植术后中远期并发症及其转归。方法收集69例(3例为再次肝移植)肝移植患者的临床及随访资料。分析生存率和术后死亡原因,观察中远期并发症发生率及其转归。结果 69例患者术后总1、3和5年累计生存率分别为94.0%、76.6%及73.3%,其中良性疾病者分别为96.7%、89.9%及89.9%,恶性疾病者分别为91.9%、65.1%及59.2%。良、恶性组间累计生存率差异有统计学意义(<0.05)。术后死亡22例中有17例死于肿瘤复发。中远期主要并发症有慢性排斥反应、迟发性急性排斥反应、胆道并发症、门静脉血栓、精神并发症、乙型肝炎复发及肿瘤复发等。结论肿瘤复发、急慢性排斥反应和胆道并发症是影响肝移植术后长期存活的主要原因。严格掌握肝移植的指征,早期发现并积极治疗各种并发症可改善预后。
出处 《现代实用医学》 2011年第7期743-745,共3页 Modern Practical Medicine
  • 相关文献

参考文献4

二级参考文献15

  • 1Parkin DM,Bray F,Ferlay J,et al.Global cancer statistics,2002.CA Cancer J Clin,2005,55:74-108.
  • 2Tang ZY,Ye SL,Liu YK,et al.A decade's studies on metastasis of hepatocellular carcinoma.J Cancer Res Clin Oncol,2004,130:187-196.
  • 3Mazzaferro V,Regalia E,Doci R,et al.Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis.N Engl J Med,1996,334:693-699.
  • 4Leung JY,Zhu AX,Gordon FD,et al.Liver transplantation outcomes for early-stage hepatocellular carcinoma:results of a multicenter study.Liver Transpl,2004,10:1343-1354.
  • 5Khakhar A,Solano E,Stell D,et al.Survival after liver transplantation for hepatocellular carcinoma.Transplant Proc,2003,35:2438-2441.
  • 6Fernandez JA,Robles R,Marin C,et al.Can we expand the indications for liver transplantation among hepatocellular carcinoma patients with increased tumor size? Transplant Proc,2003,35:1818-1820.
  • 7Lee KW,Park JW,Joh JW,et al.Can we expand the milan criteria for hepatocellular carcinoma in living donor liver transplantation? Transplant Proc,2004,36:2289-2290.
  • 8Marsh JW,Dvorchik I,Bonham CA,et al.Is the pathologic TNM staging system for patients with hepatoma predictive of outcome? Cancer,2000,88:538-543.
  • 9Yao FY,Ferrell L,Bass NM,et al.Liver transplantation for hepatocellular carcinoma:expansion of the tumor size limits does not adversely impact survival.Hepatology,2001,33:1394-1403.
  • 10Shetty K,Timmins K,Brensinger C,et al.Liver transplantation for hepatocellular carcinoma validation of present selection criteria in predicting outcome.Liver Transpl,2004,10:911-918.

共引文献132

同被引文献14

引证文献1

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部