蓝光光疗预防新生儿胆红素脑病(附129例报告)

PREVENTING NEONATAL BILIRUBINEMIA BY BLUE-LIGHT PHOTOTHERAPY (reported Ofh 129 cases)

本文报告129例蓝光光疗预防新生儿胆红素脑病(核黄疸)。综合分析表明,引起新生儿黄疸和核黄疸的高危因素主要是感染、窒息、酸中毒、寒冷刺激、低蛋白血症、早产、溶血症等。无论是生理性或病理性黄疸,其主要危害是胆红素透过血脑屏障渗入脑组织,引起核黄疸,严重地影响了小儿生长和智力发育,我们对有上述因素存在者,血清胆红素虽未达到高胆红素血症标准,均积极采取预防性蓝光光疗措施,避免了核黄疸发生,取得满意效果。

One hundred and twenty-nine cases treated by blue-light phototherapy to prevent neonatal bilirubinemia (kernicteras) are reported.As indicated by comprehensive analyses, the critical eactors causing jaundice and kernicteras are mainly infection, suffocation, acidosis, hot and cold stimulation, hypoproleinemia, premature delivery, and hemolysis etc..The main harm of both physiological and pathological jaundice is ooze of bilirubin into brain tissues through the protective screen between blood and brain that leads to kernicteras and affects the baby growing and intelligence development severely.The kernicteras can be prevented by active treatment of bluelight phototherapy to neonates who are involved in the critical factors as mentioned above though the bilirubin in serum has not reached the high level of severe neonatal bilirubinemia.The results are very satisfactory.