国产与进口鲑鱼降钙素治疗PMOP的疗效与经济比较

Curative Effect and Economic Comparison between Domestic and Import Salmon Calcitonin in Treatment of PMOP

目的比较国产与进口鲑鱼降钙素治疗绝经后骨质疏松症(postmenopausal osteoporosis,PMOP)的疗效及经济。方法 60例PMOP患者分成观察组和对照组。对照组:进口鲑鱼降钙素注射液+维生素D钙咀嚼片;观察组:国产鲑鱼降钙素注射液+维生素D钙咀嚼片。结果对照组显效率60.00%、有效率30.00%、无效率10.00%,与观察组显效率56.67%、有效率36.67%、无效率6.67%比较,差异均无显著性(P>0.05);治疗前与治疗后两组患者骨密度比较,差异无显著性(P>0.05);两组不良反应发生率差异无显著性(P>0.05)。国产鲑鱼降钙素注射液价格要明显低于进口鲑鱼降钙素注射液。结论国产鲑鱼降钙素注射液联合维生素D钙咀嚼片治疗PMOP患者疗效可靠、安全,而且经济实惠,值得临床应用推广。

Objective To compare the curative effect and economic between Domestic and Import salmon calcitonin treatment of postmenopausal osteoporosis （ PMOP ）. Methods All 60 cases of PMOP divided into observation group and control group. Control group： Import salmon calcitonin＋calcium supplement with Vitamin D chewable tablets; Observation Group： Domestic salmon calcitonin＋ calcium supplement-with Vitamin D chewable tablets. Results The control group： significant efficiency, efficient, inefficient were 60.00%, 30.00%, 10.00%, respectively; The observation group： significant efficiency, efficient, inefficient were 56.67%,36.67%,6.67%, respectively. There was no significant difference between two groups （P 〉 0.05 ）. Before treatment and therapy compared with after treatment, there was no significance difference in BMD between two groups （ P 〉 0.05 ）. Adverse reaction rate of two groups was no significant difference （P 〉 0.05 ）. Domestic salmon calcitonin injection price was cheaper than imported salmon calcitonin injection. Conclusion Domestic salmon calcitonin and calcium supplement with Vitamin D chewable tablets treatment of PMOP is good efficacy, fewer adverse reactions, affordable.