氯诺昔康在腹腔镜胆囊切除术中的应用

Lornoxicam in Laparoscopic Cholecystectomy

目的观察腹腔镜胆囊切除术患者氯诺昔康预防性术中给药方式的镇痛效果。方法单纯腹腔镜胆囊切除术患者60例随机分成A组(氯诺昔康组)、B组(舒芬太尼组)和C组(对照组),每组20例。所有患者在术后l、4、8、24h进行VAS评分和镇静评分,并记录有无恶心等副作用。结果术后1～4hVAS评分A组低于B组(P<0.05),各时间点明显低于C组(P<0.01)。镇静评分术后各时间点A组明显低于B组(P<0.05);与C组比较,差异无统计学意义(P>0.05)。结论氯诺昔康预防性术中给药方式的镇痛效果好且不良反应少。

Objective To observe the effect of laparoscopic cholecystectomy in patients with lornoxicam prophylactic intraoperative administration of analgesic. Methods All 60 patients who were to undergo elective laparoscopic cholecystectomy, ASA Ⅰ - Ⅱ, they were randomly divided into three groups, group A （ Lornoxicam ）, group B （ sufentanil ） and group C （ Control group ）, each group with 20 cases.All patients were rated VAS, RSS content after surgery at lh,4h,Sh,24h and various side effects such as Nausea. Results VAS score respectively 1 - 4h after surgery of group A was lower than group B （ P 〈 0.05 ）, each time point was lower than that of group C （P 〈 0.01 ）. RSS： Each time point after operation was lower in group A than group B （P 〈 0.05 ）. Compared with group C, the difference was not statistically significant （P 〉 0.05 ）. Conclusion Lornoxicam prophylactic intraoperative administration of analgesic has satisfactory effect and less side effects.