磷酸肌酸和参麦注射液治疗小儿病毒性心肌炎疗效分析

Analysis on the therapeutic effect of creatine phosphate and Shenmai injection in treatment of pediatric viral myocarditis

目的:观察磷酸肌酸(creatine phosphate,CP)和参麦注射液治疗小儿急性病毒性心肌炎的临床疗效。方法:将病毒性心肌炎住院患儿108例随机分为治疗组和对照组各54例,治疗组应用CP加常规药物、对照组则用参麦注射液加常规药物规范治疗。观察治疗前后两组患者的症状体征、心电图、心脏彩超、心肌酶谱的变化情况。结果:CP疗效显著,两组间差异有统计学意义(P<0.01)。结论:CP能更快更好地缓解症状、减少心律失常的发作、降低心肌酶、迅速恢复扩大的心脏以及明显的缩短病程。

Objective： To observe the clinical therapeutic effect of creatine phosphate and Shenmai injection in treatment of pediatric viral myocarditis. Methods： 108 hospitalized children with viral myocarditis were divided into treatment group and control group, 54 children in each group, the children in treatment group were treated with creatine phosphate and routine drugs, while the children in control group were treated with Shenmai injection and routine drugs. The symptoms, signs, results of electrocardiogram, results of cardiac ultrasonography and the changes of myocardial zymogram before and after treatment were observed. Results： The therapeutic effect of creatine phosphate was dominant, there was significant difference between the two groups （P 〈 0. 01 ） . Conclusion： Creatine phosphate can relieve symptoms faster and better, reduce the onset of arrhythmia and myocardial enzymes levels, restore the enlarged heart quickly and shorten the course of disease apparently.