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靶控输注全凭静脉全麻对老年患者脑氧供需平衡及术后认知功能的影响 被引量:4

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摘要 目的比较丙泊酚、瑞芬太尼靶控输注(TCI)全凭静脉全麻与吸入异氟醚全麻对老年患者脑氧供需平衡及术后认知功能的影响。方法 60例行腹部手术的老年患者,随机分为A组:TCI组(n=32),B组:吸入组(n=28)。分别对两组患者于术前1天、术后6h、术后1天、术后3天应用MMSE量表测试认知功能,分别于术前、手术2h、术毕、术后6h、术后24h采颈静脉球血检测并计算CjvO2、Ca-jvO2、CEO2含量。结果 A组患者术后清醒时间、肌松恢复时间,拔管时间均早于B组(P<0.05);B组在术毕、术后6h与术前比较Ca-jvO2、CEO2值均显著降低(P<0.01),A组相同时点与术前相比Ca-jvO2、CEO2降低,但无统计学意义(P>0.05);A组MMSE评分术后6h与术前相比较,差异有统计学意义(P<0.05),B组MMSE评分术后6h、术后1天与术前比较,差异有统计学意义(P<0.05)。结论丙泊酚、瑞芬太尼TCI全麻比异氟醚吸入全麻对老年患者脑氧代谢平衡和术后认知功能影响较轻,更适合老年患者麻醉。
出处 《首都医药》 2011年第18期33-34,共2页 Capital Medicine
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参考文献8

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共引文献152

同被引文献28

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