861例肾活检临床病理分析

Clinical Pathological Analysis of 861 Renal Biopsy

目的分析861例肾活检病理结果,以了解肾脏疾病的病理类型及其特点。方法回顾性分析2008-01～2009-01间,861例因肾脏疾病行肾活检的病理资料,并进行统计和总结。结果 861例患者中,原发性肾小球疾病占85.6%,继发性肾小球病占13.4%,小管间质性疾病占0.8%,肾移植相关肾脏疾病占0.2%。原发性肾小球疾病中,以IgA肾病(IgAN)最多,占21.5%;其次,分别为系膜增生性肾小球肾炎占19.5%,轻微肾小球病变占17%,微小病变占11.7%,膜性肾病占9.6%;继发性肾小球疾病中,以狼疮性肾炎(LN)多见,占6.2%;其次,是乙肝相关性肾炎占3.1%,糖尿病肾病占1.4%。结论原发性肾小球疾病是最常见的肾小球病,其中以IgA肾病为主。继发性肾小球疾病以狼疮性肾炎为主。

Objective To retrospectively summarize the renal pathological entities from 861 cases of renal biopsy.To survey features and pathological types of glomerular diseases.Methods Between January 2008 to January 2009,861 cases of percutaneous renal biopsy were performed.The pathologic entities were analyzed retrospectively and the clinical pathological characteristics of renal diseases were concluded.Results Primary glomerular diseases accounted for 85.6%.Secondary glomerular diseases accounted for 13.4%,interstitial nephritis 0.8%,transplant nephropathy 0.2%.In primary glomerular diseases,IgA nephropathy,mesangial proliferative glomerulonephritis,minor glomerular abnormalities,minimal change disease,membrane nephropathy,was accounted for 21.5%,19.5%,17%,11.7%,9.6%,respectively.In secondary glomerular diseases,lupus nephritis,HBV-associated nephritis,diabetic nephropathy,accounted for 6.2%,3.1%,1.4%.Conclusion Primary glomerular disease was the most common renal disease occrurred in patients.IgA was predominant.LN was the most common in secondary glomerular diseases.