环酯红霉素与洛美沙星治疗女性生殖道沙眼衣原体感染疗效观察

Observation on Curative Effect of Female Genital Bedsonia Trachomatis Infection Treated with Cyclic Ester and Lomefloxacin

目的探讨环酯红霉素治疗女性生殖道沙眼衣原体感染的疗效。方法将125例分为两组:环酯红霉素组65例,口服环酯红霉素500 mg,2次/d,疗程10 d;洛美沙星组60例,口服洛美沙星200 mg,2次/d,疗程10 d。合并淋球菌感染者,同时给予罗氏芬1.0 g,肌注,1次/d,疗程5 d。结果环酯红霉素有效率为81.5%,洛美沙星组有效率58.3%,两组比较差异有显著性(P<0.05)。结论环酯红霉素疗效明显优于洛美沙星,可以成为女性生殖道沙眼衣原体感染的首选药物。

Objective To investigate the effect of cyclic ester of erythromycin treatment for female genital chlamydia trachomatis infection.Methods Cyclic ester erythromycin group,oral erythromycin cyclic ester 500 mg,bid,10 days of treatment;lomefloxacin group,oral lomefloxacin 200 mg,bid,10 days of treatment;combined with gonococcal infection,Rocephin 1.0 g intramuscular injection,qd,5 days of treatment.Results Cyclic ester of erythromycin was 81.5% efficient,lomefloxacin group was 58.3% efficient,the statistical difference was significant（P0.05）.Conclusion Cyclic ester of erythromycin was significantly better than lomefloxacin,can be the first choice of female genital tract Chlamydia trachomatis infection.