摘要
动脉硬化性血栓性疾病是目前全球范围内致死和致残的重要原因,鉴于血小板的激活和聚集在动脉血栓形成过程中的核心作用,以阿司匹林和氯吡格雷为代表的抗血小板药物在急性冠状动脉(冠脉)综合征(ACS)、缺血性卒中等动脉血栓性疾病的治疗中获得了广泛的应用并被证实能显著改善患者的预后,其中阿司匹林和氯吡格雷双重抗血小板治疗已被公认是ACS及经皮冠脉介入治疗(PCI)患者的标准方法。
出处
《中华内科杂志》
CAS
CSCD
北大核心
2011年第9期794-796,共3页
Chinese Journal of Internal Medicine
参考文献31
-
1Anderson JL, Adams CD, Antman EM, et al. ACC/AHA 2007 guidelines for the management of patients with unstable angina/ non-ST-Elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction ) developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine. J Am Coll Cardiol, 2007, 50 : e1-e157.
-
2Sacco RL, Adams R, Albers G, et al. Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke : co-sponsored by the Council on Cardiovascular Radiology and Intervention : the American Academy of Neurology affirms the value of this guideline. Circulation, 2006, 113 : e409-e449.
-
3King SB 3rd, Smith SC Jr, Hirshfeld JW Jr, et al. 2007 Focused Update of the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: 2007 Writing Group to Review New Evidence and Update the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention, Writing on Behalf of the 2005 Writing Committee. Circulation, 2008, 117 : 261-295.
-
4Lanas A, Garcia-Rodriguez LA, Arroyo MT, et al. Effect of antiseeretory drugs and nitrates on the risk of ulcer bleeding associated with nonsteroidal anti-inflammatory drugs, antiplatelet agents, and anticoagulants. Am J Gastroenterol, 2007, 102:507- 515.
-
5Ho PM, Maddox TM, Wang L, et al. Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome. JAMA, 2009, 301 : 937-944.
-
6Angiolillo DJ. Variability in responsiveness to oral antiplatelet therapy. Am J Cardiol, 2009,103(3 Suppl) :27A-34A.
-
7Coccheri S. Antiplatelet drugs-do we need new options? With a reappraisal of direct thromboxane inhibitors. Drugs, 2010, 70 : 887-908.
-
8Maree AO, Fitzgerald DJ. Variable platelet response to aspirin and clopidogrel in atherothrombotic disease. Circulation, 2007, 115 : 2196-2207.
-
9Maree AO, Curtin RJ, Chubb A, et al. Cyclooxygenase-1 haplotype modulates platelet response to aspirin. J Thromb Haemost, 2005, 3:2340-2345.
-
10Simon T, Verstuyft C, Mary-Krause M, et al. Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med, 2009, 360: 363-375.
同被引文献45
-
1European Stroke Organisarion (ESO) Executive Committee;ESO Writing Committee.Guidelines for management of ischaemic stroke and transient ischaemic attack 2008[J]Cerebrovascular Diseases,2008(05):457-507.
-
2Hill MD;Silver FL;Austin PC.Rate of stroke recurrence in patients with primary intracerebral hemorrhage[J]Stroke,2000(01):123-127.
-
3He J;Whelton PK;Vu B.Aspirin and risk of hemorrhagic stroke-a meta-analysis of randomized controlled trials[J]Journal of the American Medical Association,1998(22):1930-1935.
-
4Saloheimo P;Ahonen M;Juvela S.Regular aspirin-use preceding the onset of primary intracerebral hemorrhage is an independent predictor for death[J]Stroke,2006(01):129-133.
-
5Ishibashi A;Yokokura Y;Adachi H.ls antiplatelet therapy for the prevention of ischemic stroke associated with the prognosis of mtracerebral hemorrhagc[J]Kurume Medical Journal,2008(3-4):71-75.
-
6Naidech AM;Jovanovic B;Liebling S.Reduced plagelet activity is associated with early clot growth and worse 3-month outcome after intracerebral hemorrhage[J]Stroke,2009(07):2398-2401.
-
7Naidech AM;Bemstein R;Levasseur K.Platelet activity and outcome after intracerebral hemorrhage[J]Annals of Neurology,2009(03):352-356.
-
8Huang Y;Cheng Y;Wu J.Cilostazol as an alternative to aspirin after ischaemic stroke:a randomised,double,blind,pilot study[J]Lancet Neurology,2008(06):494-499.
-
9Eckman MH;Rosand J;Knudsen KA.Can patients be anticoagulated after intracerebral hemorrhage? A decision analysis[J]Stroke,2003(07):1710-1716.
-
10黄东芳,赵子彦.阿司匹林在高血压中的应用进展[J].山东医药,2008,48(13):116-116. 被引量:7
引证文献5
-
1高旭光.抗栓治疗对脑出血血肿扩大和再出血的影响[J].中国医学前沿杂志(电子版),2012,4(4):22-24. 被引量:3
-
2廖承广,吴智珊,徐小琴.阿司匹林时间治疗降压作用的研究[J].西部医学,2014,26(3):310-313. 被引量:2
-
3廖承广,吴智珊,徐小琴.阿司匹林服药时间对老年原发性高血压患者血压控制效果的影响[J].海南医学,2014,25(11):1651-1653. 被引量:7
-
4陈丹丹,于楠.新型抗血小板药物的研究进展[J].海峡药学,2018,30(1):95-98. 被引量:9
-
5孙国民.阿司匹林联合氯吡格雷治疗进展性缺血性脑卒中的效果评价[J].中国处方药,2017,15(10):51-52. 被引量:4
二级引证文献25
-
1陈馨,李彩文,李贵良,赵东亚,刘秀杰.3-芳酰氨基-4-甲氧基苯甲酰胺类化合物的合成及体外抗血小板聚集活性研究[J].中国药物化学杂志,2020,30(3):136-141.
-
2彭智祥,李雪,王亚敏,赵诗云,吴东风,张娣.天然产物抗血小板聚集作用的研究进展[J].沈阳药科大学学报,2019,36(12):1133-1144. 被引量:5
-
3仇凯,陈馨,刘秀杰.4-甲氧基-1,3-苯二磺酰胺系列化合物的合成及体外抗血小板聚集活性的研究[J].沈阳药科大学学报,2019,36(12):1082-1086.
-
4大垣,阳二,秋保,庆志,宅和,稔朗,廖建国.高炉喷吹废塑料的预处理技术[J].浙江冶金,2000(1):24-26. 被引量:1
-
5马更平,康全利,陈善文.不同手术时机治疗高血压脑出血的疗效及对预后的影响[J].中国临床医生杂志,2015,43(3):52-54. 被引量:21
-
6孙卫平,李春蕾,温宇梅,张海滨,张学坤,郭金城.冠状动脉粥样硬化性心脏病患者早上和睡前服用阿司匹林的临床效果[J].四川医学,2015,36(6):835-837. 被引量:5
-
7迟相林.动脉血压的形成[J].中华高血压杂志,2015,23(8):786-789. 被引量:7
-
8迟相林,毕建忠,许顺良,鞠卫萍.再谈缺血性脑卒中的血压管理[J].中华高血压杂志,2015,23(9):817-819. 被引量:8
-
9胡火有,韩漫夫,肖小华.既往脑出血患者脑梗死急性期抗栓治疗安全性分析[J].辽宁医学杂志,2016,30(2):9-10.
-
10胡火有.脑出血患者脑梗死急性期抗栓治疗安全性回顾性分析[J].深圳中西医结合杂志,2016,26(8):20-21. 被引量:1
-
1杨跃进,戴军.预防脑血栓可长期服用阿司匹林[J].家庭用药,2009(1):19-19.
-
2韩凤波.氯吡格雷临床应用进展[J].中国煤炭工业医学杂志,2007,10(4):369-370. 被引量:4
-
3阿司匹林在动脉硬化性主血管疾病中的临床应用中国专家共识会在北京举行[J].中国社区医师,2006,22(4):9-9.
-
4叶冬梅,黄桂莉,兰顺.七种常用降脂药物的成本效果分析[J].广西医学,2001,23(1):133-135. 被引量:1
-
5韩凤波.氯吡格雷应用进展[J].山西医学教育,2006(2):33-35.
-
6周法根,胡弘煜.1,6-2磷酸果糖治疗动脉硬化性脑梗塞临床观察[J].浙江中西医结合杂志,1996,6(2):71-72. 被引量:1
-
7高英,王国团,范太根.氯吡格雷临床应用进展[J].中国实用神经疾病杂志,2009,12(1):92-94. 被引量:21
-
8黄华,张立君.辅用抗生素治疗冠心病100例疗效观察[J].山东医药,2001,41(14):71-71.
-
9金仲品.动脉硬化性高血压病人怎样服用阿司匹林[J].家庭医学(上半月),2008(8):28-28.
-
10李小鹰.远离心脑血管病[J].大众医学,2007(7):67-67.