电针配合药物治疗抑郁症疗效观察

Clinical observation on depression treated by electroacupuncture combined with western medicine

目的:评价针刺及电针结合药物治疗抑郁症的临床疗效。方法:75例抑郁症患者随机分为3组,对照组(30例)单纯口服5-羟色胺再摄取抑制剂(SSRI)类药物治疗;观察1组(25例)采用针刺配合SSRI类药物治疗,针刺取百会、印堂、神庭、大椎、神道、至阳等,行导气针法;观察2组(20例)采用电针配合SSRI类药物治疗,取穴同观察1组,行常规针刺,百会、印堂等加电针。分别观察各组临床疗效和治疗1、2、4、6周后汉密尔顿(HAMD)量表总评分情况。结果:观察1组(25/25)、观察2组(20/20)有效率均为100.0%,均优于对照组的73.3%(22/30)(均P<0.05)。各组治疗后各时间点HAMD总分与治疗前比较,均呈下降趋势(P<0.01,P<0.05);其中观察1组、观察2组在治疗1、2、4周后HAMD总分改善明显优于对照组(P<0.01,P<0.001),而在治疗6周后差异无统计学意义(均P>0.05)。治疗1周后,HAMD总分观察2组低于观察1组(P<0.05),治疗2、4、6周后,两组比较差异无统计学意义(均P>0.05)。结论:针刺及电针结合药物治疗抑郁症疗效好,优于单用药物治疗;而针刺及电针疗效比较无差异,但电针起效快。

Objective To evaluate the clinical therapeutic effect of depression treated by acupuncture and electroacupuncture combined with western medicine.Methods Seventy-five patients were randomly divided into 3 groups.In control group,30 cases were treated by SSRI with oral administration;in observation group 1,25 cases were treated by acupuncture therapy combined with SSRI,and Shenting（GV 24）,Baihui（GV 20）,Dazhui（GV 14）,Shendao（GV 11） and Zhiyang（GV 9） etc.were selected with regulating qi needling method;in observation group 2,same acupoints were selected with routine needling method,and 20 cases were treated by electroacupuncture therapy combined with SSRI,Baihui（GV 20） and Yintang（EX-HN 3） etc.were treated by electroacupuncture.The clinical therapeutic effects and Hamilton Depression Scale scores were evaluated after 1,2,4 and 6 weeks treatment.Results The total effective rates of observation group 1 and 2 were 100.0%,superior to that of 73.3% in control group（both P〈0.05）.The total scores of HAMD on each time point dropped,and there were significant differences compard with those before treatment in 3 groups（P〈0.01,P〈0.05）;the total scores of HAMD after 1,2 and 4 weeks improved more obviously than that in control group（P〈0.01,P〈0.05）,and there was no significant difference among groups after 6 weeks（all P〈0.05）.After one week treatment,the comparison of total scores of HAMD in observation group 1and 2 indicated significant differences（P〈0.05）;after 2,4 and 6 weeks treatment,there were no significant differences between groups（all P〈0.05）.Conclusion The acupuncture therapy and electroacupuncture combined with western medicine for treating depression have better effects than medicine treatment;and there is no obvious difference between acupuncture therapy and electroacupuncture therapy,however,the effect works fast by electroacupuncture.