西比灵联合地巴唑治疗血管神经性头痛的疗效观察

Efficacy observation of Sibelium combined Dibazol in treatment of vascular tension headaches

目的:观察西比灵与地巴唑联合治疗血管神经性头痛的临床疗效,为今后临床治疗提供依据。方法:选择2005年10月～2010年10月在我院就诊的血管神经性头痛患者184例,将其随机分为A、B两组,每组92例。A组患者采用口服西比灵加地巴唑治疗,B组患者采用口服西比灵的方法进行治疗。对两组治疗效果、不良反应、并发症、毒副作用进行观察,对A组治疗前后的血液流动速度和血流动力学变化进行比较分析。结果:A组患者在治疗前后血流动力学和脑部血流速度都有明显改变,前后差异有统计学意义(P<0.05),其临床治疗效果明显优于B组,差异有统计学意义(P<0.05)。结论:西比灵与地巴唑联合治疗血管神经性头痛患者临床疗效明显,对血流动力学和脑部血流速度有显著的改善作用,毒副作用小,用药后几乎没有不良反应和并发症出现,值得临床推广。

Objective： To observe the efficacy of Sibelium combined Dibazol in treatment of vascular tension headaches and provide reliable basis for clinical treatment. Methods： 184 cases of vascular tension headaches from October 2005 to October 2010 in our hospital were randomly divided into group A （92 cases） and group B （92 cases）. Patients in group A were given Sibelium combined Dibazol oral treatment, patients in group B were given Sibelium oral. The clinical treatment efficacy, adverse reactions, complications and side effects of two groups were observed, and blood flow velocity and hemodynamics changes of group A were analyzed before and after treatment. Blood flow velocity and hemodynamics of group A had obvious changes, before and after treatment, the difference was statistically significant （P〈0.05）, the clinical treatment effect of group A was better than group B, the difference was statistically significant （P〈0.05）. Conclusion： Efficacy of Sibelium combined Dibazol in treatment of vascular tension headaches is obvious, it can change blood flow velocity and hemodynamics effectively, toxic side effects is low and there is no obvious adverse reactions and complications, so it is worthy of clinical application.