α-细辛脑治疗癫痫114例

α-Asarone in the treatment of epilepsy in 114 patients

应用合成的α-细辛脑60mg,tid(>15yr)或30mg,tid(≤15yr)治疗各种类型癫痫发作114例,并与性别、年龄、病因、临床发作类型和病程相似的57例苯妥因治疗的对照组进行比较;结果发现α-细辛脑有与苯妥因相似的疗效,尤其对于病程短的大发作疗效更佳,可作为癫痫初发患者的首选药物之一。

The authors report their experience in 114 patients with various types of epilepsy treated with a-asarone with a dosage 60 mg tid(>15 yr)or 30 mg, tid (15 yr) 57 patients treated with phenytoin 0.1 bid or tid as control. They all got a similar success. The patients in these two groups had a general likeness in their age, sex, etiology, duration and types of seizures. It is suggested that a-asarone may be the drug of choice for these particular grand mal epilepsy-patients.