甲型H1N1流行性感冒临床分析

H1N1 Influenza Flu:Report of 130 Cases

目的探讨甲型H1N1流行性感冒(流感)的诊断、治疗要点。方法回顾性分析130例甲型H1N1流感患者的临床特点、治疗方法。结果病情轻的甲型H1N1流感患者给予中成药连花清瘟胶囊对症、支持治疗有效;病情重合并感染者给予抗感染中药对症、支持治疗基础上,加用神经氨酸酶抑制剂奥司他韦抗病毒治疗有效。130例患者治疗前后白细胞计数、淋巴细胞分数、中性粒细胞分数、血小板计数比较,差异均有统计学意义(P<0.05)。结论甲型H1N1流感传播广而迅猛,人群普遍易感。抗病毒(神经氨酸酶抑制剂奥司他韦)、中成药(连花清瘟胶囊)及对症支持治疗合并感染者有效。

Objective To explore the diagnosis and treatment of H1 N1 pandemic influenza. Methods Clinical characteristics and treatment of 130 cases of H1N1 influenza were retrospectively analyzed. Results Patients with mild H1N1 flu re- sponsed to the supportive treatment by traditional Chinese medicine, Lianhuaqingwen capsule while severe patients with compli- cated infections responsed to combined anti - infection traditional Chinese medicine therapy, supportive treatment, and oseltami- vir, an anti -influenza virus neuraminidase inhibitor. Comparison of WBC count, lymphocyte fraction, neutrophil fraction, and platelet count between before and after treatment showed significant differences （P 〈 0. 05） . Conclusion H1N1 pandemic in- fluenza spread widely and rapidly, which were easily be infected. Combination of anti - infection traditional Chinese medicine therapy, supportive treatment, and oseltamivir is effective in treating H1N1 flu with complicated infections.