编码荧光微/纳米颗粒制备及应用进展

Development of preparation and application of encoding fluorescent micro/nanoparticles

编码荧光微/纳米颗粒作为一类特殊的功能颗粒,以其稳定的形态结构、均匀的粒径分布、良好的单分散性、极高的荧光量子产率和良好的界面反应性等特性,在许多领域特别是生物医学领域具有广泛的应用前景,引起了国内外众多学者的广泛关注。但是在国内研究制备技术不成熟,应用的颗粒探针多依赖进口,如何能使编码荧光微/纳米颗粒国产化,将对我国生物医学等领域的发展具有重要意义。主要对编码荧光微/纳米颗粒的定义、组成、分类、制备技术及其应用进行了综述,并对其应用研究前景进行了展望。

Encoding fluorescent micro/nanoparticles, one kind of functional particles, have attracted more attention of researchers and been used in many fields especially in biomedicine because of their hard shape, narrower particle size distribution, good monodispersivity and high photoluminescent quantum yield （PLQY）. However, the development situation of preparing technologies of encoding fluorescent micro/nanoparticles is far from enough in our country, and the products used are mainly imported from other countries. It will be an great importance for the development of our biomedical and other fields by applying nationalized encoding fluorescent micro/ nanoparticles. The definition, categories, composition and preparing technologies of encoding fluorescent micro/ nanopartiele are introduced as a very important part. In the end, the development in the research and application of encoding fluorescent micro/nanoparticles is anticipated.