氧化法合成非索非那定吡啶盐及其机理研究(英文)

A Novel Synthesis of Fexofenadine Pyridinium Salts by Oxidation of Piperidine Derivatives under Simple Conditions

报道了一种用简单氧化剂将哌啶衍生物氧化为相应吡啶盐的方法,该方法具有反应条件温和、产率高等优点,并对反应机理进行了研究探讨.

The paper reported an efficient synthetic procedure, which has mild response conditions and high productivity, for the preparation of some novel pyridinium salts by oxidation of piperidine derivatives only using some simple oxidants in high yield at ambient temperature and researches on its response mechanisms.