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垂体后叶素诱发低钠血症及水中毒 被引量:3

Posterior pituitary hormone induced hyponatremia and water intoxication
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摘要 本文报道6例在垂体后叶素应用过程中出现低钠血症及水中毒表现、包括临床表现及实验室检查。重点分析垂体后叶素引起水中毒的机理、防治的重要性及方法。 In managing the hemorrhage form alimentary tract in 6 patients with posterior pituitary hormone, hyponatremia and water intoxication is worthwhile to pay attention to. In these patients, the sodium concentration of blood fell below 120 mmol/L, and that of urine above 20 mmol/L. The imbalance of electrolyte caused cerebral edema with mental disorder or unconsciousness in dominance might mislead into cerebral diseases. To withdraw the causative remedy and to restrict the fluid intake not more than 1500 ml/d should be specially emphasized.
出处 《新药与临床》 CSCD 北大核心 1990年第4期243-245,共3页
关键词 垂体后叶激素 血钠过少 水中毒 posterior pituitary hormone hyponatremia electrolyte imbalance
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  • 1王艳,王早堂.垂体后叶素致严重低钠性脑病1例报告[J].华南国防医学杂志,2003,17(4). 被引量:2
  • 2顾美娣 于晓峰 顾同进.脑垂体后叶素持续静脉滴注引起老年人抗利尿激素作用[J].中华结核和呼吸杂志,1991,14(1):56-56.
  • 3国家药典委员会编.临床用药须知(第3版)[M].化学工业出版社,2001年4月.p740.
  • 4贾欣增 李培杰.脑垂体后叶素引起稀释性低钠血症一例[J].兰州医学院学报,1986,(2):81-81.
  • 5丁慧昌.静注脑垂体后叶素出现重度低渗血症3例[J].药物流行病学杂志,1995,4(2):121-121.
  • 6Odeh M, Oliven A. Coma and seizures due to severe hyponatremia and water intoxication in an adult with intranasal desmopressin therapy for nocturnal enuresis. J Clin Pharmacol, 2001,41 (5): 582.
  • 7Amelsvoort TV, Bakshi R, Devaux CB, et al. Hyponatremia associated with carbamazepine and oxcarbazepine therapy: a review. Epilepsia, 1994,35(1): 181.
  • 8Ryan M, Adams AG, Larive LL. Hyponatremia and leukopenia associated with oxcarbazepine following carbamazepine therapy. Am J Health-Syst Pharm. 2001, 58(17) :1637.
  • 9Odeh M, Seligmann H, Oliven A. Severe life-threatening hyponatremia during paroxetine therapy. J Clin Pharmacol, 1999,39(12) :1290.
  • 10Oglvie AD, Croy MF.Clazapine and hyponatremia.Lancet, 1992,340: 672.

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