摘要
目的:探讨多囊卵巢综合征痰湿证临床及性激素、抗苗勒氏管激素(AMH)的特征性,从而为多囊卵巢综合征的中医规范化诊治提供依据。方法:以50例正常育龄妇女为对照组,150例PCOS患者分为两组:非痰湿组、痰湿组,其中非痰湿组99例,痰湿组51例,化学发光法测定血清性激素水平及AMH水平,同时比较3组初潮年龄、月经周期、BMI、腰围、SBP、DBP等临床指标的差异性。结果:①各组间临床特征比较:月经周期PCOS两组与对照组比较均有显著性差异(P<0.05);BMI、腰围PCOS痰湿组与对照组及非痰湿组比较均有显著性差异(P<0.05)。②各组间性激素及AMH的比较:LH、T、AMH值PCOS两组与对照组比较均有显著性差异(P<0.05);血清AMH值PCOS两组间比较也有显著性差异(P<0.05)。结论:多囊卵巢综合征痰湿证在BMI、腰围、AMH等水平具有特征性表达,提示痰湿证有胰岛素抵抗的倾向性。
Objective:To explore the characteristics of sex hormone and Anti -Miillerian hormone (AMH)in PCOS pa- tients with phlegm -dampness in order to give further basis on standardized diagnosis and teatment of PCOS. Methods :50 normal reproductive- aged women as controls, and 150 PCOS patients were divided into two groups: phlegm- dampness group and non phlegm- dampness group. Serum sex hormone, as well as AMH levels were measured by Chemilumines- cence. Indeics above and other parameters ( menstrual cycle, BMI, waist size, etc were compared among groups. Results : (1)clinical characteristics : menstrual cycle : PCOS groups 〉 control; BMI, waist size : phlegm - dampness PCOS group 〉 control, phlegm - dampness PCOS group 〉 non phlegm - dampness group (P 〈 0. 05 ). (2)sex hormone and AMH : LH, T, AMH levels: there were significant difference between PCOS groups and control, there were also significant difference of AMH between phlegm - dampness PCOS and non phlegm - dampness PCOS group ( P 〈 0. 05 ). Conclusions : There were characteristic expression on BMI, waist size, AMH in phlegm - dampness PCOS patients, they might have insulin resistance tendency.
出处
《中华中医药学刊》
CAS
2011年第9期1977-1979,共3页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金资助项目(81072758)