医院获得性尿路感染的病原菌分布及危险因素logistic回归分析

Distribution of pathogenic bacteria causing hospital-acquired urinary tract infection and logisticregression analysis of risk factors

目的了解医院获得性尿路感染的危险因素及病原菌分布特点,以制定预防和控制医院感染的方案。方法采用logistic回顾性对照分析2009年8月-2010年8月,医院内的尿路感染与非尿路感染的病例,并了解其病原菌分布,找出尿路感染的各种危险因素。结果女性、年龄≥60岁、留置尿管、置管时间>20d、患有基础疾病及住院时间>35d与获得性尿路感染的相关性,差异有统计学意义(P<0.05),尿路感染常见病原菌依次为真菌占40.85%、革兰阴性菌占34.15%、革兰阳性菌占25.00%。结论了解尿路感染的危险因素,对有效预防医院内获得性尿路感染有重要意义。

OBJECTIVE To analyze the risk factors and pathogenic distribution in patients who had hospital-acquired urinary tract infections,and to develop program for prevention and control of hospital infection.METHODS The cases with or without urinary tract infections hospitalized between Aug 2009 and Aug 2010 were retrospectively studied.The pathogen distribution and the risk factors for hospital-acquired urinary tract infections were analyzed by logistic regression.RESULTS The results revealed that the female aged≥60 years,indwelling catheterization,and indwelling time〉 20d,with the primary diseases and the hospitalization〉35d were significantly correlated with hospital-acquired urinary tract infections（P〈0.05）.The most common pathogens were fungi,accounting for 40.85%,followed by Gram-negative bacteria（34.15%） and Gram-positive bacteria（25.00%）.CONCLUSION Better understand the risk factors for urinary tract infection has great significance for the effective prevention of hospital-acquired urinary tract infection.