乳腺Ⅰ类切口围手术期抗菌药物应用分析

Antibiotics application for type Ⅰ incision of breast surgery during perioperative period

目的探讨乳腺手术Ⅰ类切口围手术期抗菌药物的合理使用。方法选择357例乳腺Ⅰ类切口择期手术病例,将2010年3-8月179例和2008年3-8月178例病例分别作为试验组与对照组,比较预防性用药种类、疗程、用药费用及医院感染率。结果试验组围手术期不使用抗菌药物者占55.31%,仅术前30min～2h用药1次者占44.69%;试验组抗菌药物均选择Ⅰ、Ⅱ代头孢菌素,对照组Ⅰ、Ⅱ代头孢菌素分别占4.50%和9.55%;试验组与对照组平均抗菌药物费用两组差异有统计学意义。结论乳腺Ⅰ类切口围手术期不使用抗菌药物或仅术前用药1次,并未增加切口感染率及其他部位感染率,降低了患者医疗费用。

OBJECTIVE To study the reasonable antibiotics application for type Ⅰ incision of breast surgery during perioperative period.METHODS A total of 357 type I incision of breast surgery were collected.179 cases from Mar to Aug 2010 and 178 cases from Mar to Aug 2008 were regarded as test group and control group respectively,the effects of different antibiotics,drug using duration,charge and nosocomial infection between the two groups were compared.RESULTS 55.31% patiants didn＇t use antibiotics,and were used only once in 44.69% 30min to 2 hours before the surgery during perioperative period in test group.The first and second generation Cephalosporin used accounted for 100.00% in test group,while 4.50% and 9.55% in control group respectively.The difference of fee on antibiotics between the two groups was statistically significant.CONCLUSION Antibiotics are not used in type Ⅰ incision of breast surgery during perioperative period,or are used only once before surgery.It does not increase infection incidence of operation sites and others,while the fee decreases.