515例妇女高危型HPV感染检测结果分析

Case Study of 515 Women with High-risk Human Papillomavirus Infection

目的:了解高危型人乳头瘤病毒(HPV)在妇女中的感染情况方法:将健康体检妇女以年龄40岁为界分为2个实验组:低年龄组(<40岁)和高年龄组(≥40岁),应用高危型人乳头瘤病毒多重核酸扩增荧光定量检测技术对5 1 5例健康体检妇女进行高危型HPV感染检测,比较低年龄组和高年龄组之间高危型HPV感染情况,对结果进行统计学分析。结果:515例健康体检妇女中,高危型HPV感染总阳性率为8.54%(44/515),低年龄组和高年龄组高危型HPV感染率分别为3.45%(3/87)和9.58%(41/428),高年龄组高危型HPV感染阳性率高于低年龄组(P<0.05),高危型HPV感染阳性率在40岁以上妇女感染率较高结论:40岁以上妇女为高危型HPV感染高发人群,加强高危型HPV检测对降低该人群宫颈癌的发生率和致死率至关重要。

Objective： To investigate the infection status of high-risk human papillomavirus （ HPV ） in women. Methods： The study group consisting of 515 healthy women was divided into two experimental groups. One was the low-age group （ 〈40 years old ）, and the other was the high-age group （ ≥40 years old ）. The infection status of high-risk HPV was determined by the multiplex polymerase chain reaction fluorescence detection technology. The results of the two groups were compared and statistically analyzed, Results： The total high-risk HPV-positive rate for the entire study group was 8.54% （ 44/515 ）. The positive rate was 3.45% （ 3/87 ） for the low-age group, and 9.58% （ 41/428 ） for the high age group （ P〈 0.05 ）. Conclusion： Women over 40 years old have a high risk for high-risk HPV infection. High-risk HPV detection methods must be enhanced to decrease the incidence and mortality of cervical cancer in women over 40 years old.