脾动脉栓塞治疗肝硬化并脾功能亢进56例临床分析

Splenic artery embolization for liver cirrhosis and hypersplenism of 56 cases

目的:探讨脾动脉栓塞术治疗肝硬化并脾功能亢进的临床疗效及其安全性。方法:回顾性分析本院2006年2月～2010年12月收治的肝硬化并脾功能亢进患者56例的临床资料,所有患者均采用脾栓塞术治疗,观察比较术前、术后脾功能亢进改善情况及并发症的发生情况。结果:56例脾功能亢进患者行部分性脾栓塞术后总有效率为94.4%(53/56),3例效果不明显。56例患者1年后随访,2例复发,复发率为3.57%。56例患者中,术后1周时有44例患者血小板均>10.0×109/L。术后均有一定比例的并发症发生。结论:对肝硬化合并门脉高压、脾功能亢进患者实施PSE治疗,血细胞数值有不同程度升高,达到了治疗脾功能亢进的目的,消化道出血减少,提高了生存质量。

Objective： To investigate the splenic artery embolization for hypersplenism of cirrhosis and the clinical efficacy and safety. Methods： A retrospective analyzed of our hospital from February 2006 December to 2010 cirrhosis and hypersplenism treated 56 patients clinical data, all patients were treated with splenic embolization observed and compared before surgery, hypersplenism and to improve the situation the occurrence of complications. Results： 56 cases of patients with hypersplenism after partial splenic embolization total efficiency of 94.4% （53/56）, 3 cases ineffective. 56 patients after 1 year follow-up, 2 cases of recurrence, the recurrence rate of 3.57%. 56 patients, 1 week after surgery, 44 patients platelets were〉10.0×109/L. There was a certain percentage of postoperative complications. Conclusion： Cirrhosis and portal hypertension, hypersplenism treatment for patients with PSE, have different blood cell values increased, reaching the treatment of hypersplenism purposes, reduced gastrointestinal bleeding, improved quality of life.