硫辛酸联合治疗急性脑梗死的疗效观察

Clinical research of therapeutic alliance included lipoic acid to acute cerbral infarction

目的:观察硫辛酸联合其他药物治疗急性脑梗死患者的疗效。方法:将2009年1月～2010年12月在本院住院或门诊治疗的120例急性脑梗死患者,随机分为实验组和对照组各60例,实验组用硫辛酸联合阿司匹林、辛伐他汀、银杏叶提取物治疗,对照组应用阿司匹林、辛伐他汀、银杏叶提取物治疗。分别于发病后72h内、治疗2周后对两组患者进行神经功能缺损程度评分和临床疗效评定,比较两组的差异。结果:治疗后两组神经功能缺损程度评分均有明显改善,实验组优于对照组(P<0.05);治疗后两组临床疗效实验组高于对照组(P<0.05)。结论:硫辛酸有助于提高急性脑梗死患者的疗效。

Objective： To observe the curative effect of therapeutic alliance included lipoic acid to acute cerbral infarction. Methods： 120 cases of acute cerebral infarction were divided into experiment group and control group randomly, experiment group 60 cases were given lipoic acid combined with aspirin, simvastatin, ginkgo biloba leaf extract and control group 60 cases were given applied aspirin, simvastatin, ginkgo biloba leaf extract. Neurologic impairment score and curative effect were evaluated and compared within 72 hours after the onste and after 2 weeks treatment between the two groups. Results： After treatment the neurologic score had improved both in two groups significantly, it was higher in experiment group than control group （P〈0.05） and the curative effect was better in experiment group than control group （P〈0.05）. Conclusion： Lipoic acid can improve the curative effect of acute cerebral infarction.