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硼替佐米联合化疗治疗多发性骨髓瘤的临床分析 被引量:1

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摘要 多发性骨髓瘤(MM)是B细胞来源的恶性肿瘤,它影响产生免疫球蛋白的浆细胞,是血液系统第二常见恶性肿瘤。目前的传统化疗方案有效率为70%,但完全缓解(CR)率不高。新药硼替佐米是蛋白酶体抑制剂,它和多种化疗药物如地塞米松、阿霉素等联合,具有疗效叠加及协同效应,使初治MM的完全缓解或接近完全缓解(CR/nCR)率达到25%[1,2]。我们以硼替佐米为主要药物治疗了30例MM患者,观察其疗效及不良反应.现报告如下。
出处 《中国药物与临床》 CAS 2011年第9期1077-1078,共2页 Chinese Remedies & Clinics
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参考文献6

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