经肺穿刺诊断肺硬化性血管瘤临床病理分析

Sclerosing hemangiomas of lung:aclinicopathological observation

目的探讨肺硬化性血管瘤临床病理特征。方法对1例肺硬化性血管瘤的临床、病理和免疫学表型进行观察、分析及文献复习。结果肺硬化性血管瘤影像学表现为境界清楚的类圆形占位;组织学表现为瘤组织呈肺泡内出血区、腺样乳头区或片状实性区排列,瘤细胞由实质细胞和衬覆细胞两种细胞构成;免疫组织化学染色显示Ckpan,EMA在实质细胞和衬覆细胞均为阳性表达。结论肺硬化性血管瘤是一种比较少见的肺脏肿瘤,其诊断依赖于组织病理学、免疫组化,并须结合其临床资料。

Objective To investigate the clinical and pathological characteristics of sclerosing hemangioma of lung（SHL）. Methods Clinical manifestations,histological and immunohistochemical features of 1 SHL patients was analyzed retrospectively. Results SHL was well-circumscribed, type circular mass of lungs by image observation. The tumors were consisted of parenchyma cell and surface cell. These cells were arranged in haemorrhagic, papillary or sclerotic pattern. Immunohistochemistry exam showed the two type cells were positive for Ckpan and EMA. Conclusion SHL is a rare pulmonary tumor. Careful analysis of the clinicopathological features and immunohistochemisitry will be helpful to reach an accurate diagnosis.