摘要
目的探讨双输卵管梗阻患者囊胚培养后移植的妊娠结局。方法回顾分析本中心2010年1月至2010年6月因双输卵管梗阻第1次行体外受精-胚胎移植(IVF-ET)助孕患者178例(178个周期)。其中有71周期为第3天移植,作为卵裂组,107个周期为第5天移植,作为囊胚组;观察两组的妊娠结局。结果囊胚组种植率、临床妊娠率较卵裂组高,差异有统计学意义(P<0.05);而两组的流产率、宫外孕发生率、多胎率差异均无统计学意义。结论囊胚培养后移植可提高双侧输卵管梗阻患者的种植率和妊娠率。
Objective To investigate the pregnancy outcomes of blastocyst culture and transfer in patients with bilateral tubal obstruction. Methods The in vitro fertilization - embryo transfer （ IVF - ET） in 178 patients （ 178 cycles） with bilateral tubal obstruction in the center between January 2010 and June 2010 were retrospectively analyzed. Seventy - one patients （ cleavage group） received day 3 transfer , 107 patients （blastocyst group） received day 5 transfer. Pregnancy outcomes were observed in the two groups. Results Implantation rate and pregnancy rate were higher in blastocyst group than these in cleavage group （ P 〈0.05）. The miscarriage rate, ectopic pregnancy rate and multiple pregnancy rates were not significantly different between the two groups. Conclusion Blastocyst culture and transfer can improve implantation rate and pregnancy rate in patients with bilateral tubal obstruction.
出处
《临床和实验医学杂志》
2011年第17期1348-1349,共2页
Journal of Clinical and Experimental Medicine
关键词
输卵管梗阻
囊胚培养
胚胎移植
妊娠率
Tubal obstruction
Blastoeyst culture
Embryo transfer
Pregnancy
