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合成金鸡纳生物碱衍生物的简便方法 被引量：1

An Easy Method of Synthesizing Cinchona Alkaloid Derivatives
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摘要 以CaH2为缚酸剂,DMF为溶剂,金鸡纳生物碱通过3,6-二氯哒嗪或1,4-二氯-2,3-二氮杂萘桥连,高产率地合成了用作手性配体的13个金鸡纳生物碱衍生物,其结构经NMR确证。 Thirteen cinchona alkaloid derivatives as chiral ligand were synthesized from cinchona alkaloid using 3,6-dichloro-pyridazine or 1,4-dichloro-2,3-phthalazone as bridged reagent in the presence of CaH2 in DMF under mild condition. The structures were confirmed by NMR.
作者 南鹏娟 陈晶 孙晓莉
机构地区 陕西师范大学化学与材料学院 第四军医大学化学系
出处 《合成化学》 CAS CSCD 北大核心 2011年第5期667-670,共4页 Chinese Journal of Synthetic Chemistry
基金 国家自然科学基金资助项目(20973105)
关键词 金鸡纳生物碱 哒嗪 二氮杂萘 手性配体 缚酸剂 合成 cinchona alkaloid pyridazine phthalazone chiral ligand acid acceptor synthesis
分类号 O629.3 [理学—有机化学] O643.32 [理学—物理化学]
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参考文献4

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同被引文献14

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合成化学
2011年 第5期

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