中药注射剂不良反应分析

Analysis of 51 Adverse Drug Reactions Induced by Traditional Chinese Medicine Injections

目的探讨中药注射剂不良反应发生的特点,为临床合理用药提供参考。方法对我院2009年1月—2010年12月收集的51例中药注射剂不良反应进行统计、分类并分析。结果 51例中药注射剂不良反应报告中,年龄>60岁者发生不良反应比例最高(占43.14%);临床表现以皮肤及其附件损害最常见(占30.12%);涉及11个中药注射剂品种。结论临床应慎用中药注射剂,加强对中药注射剂不良反应的监测,提高用药水平。

Objective Analyzed serious adverse drug reactions （ADR） of traditional Chinese medicine injections to provide the References information for rational Drug in clinical Practice. Methods the 51 ADR reports in our hospital were counted, classified and analyzed, which were collected by clinical pharmacist in our hospital from Jan. 2009 to Dec. 2010. Results Of the 51 ADR cases, 43.14% occurred in patients aged above 60, and 30. 12% manifested as lesions of skin and ap- pendants. 51Cases involve 11 infections. Conclusion The TCM injection should be used with great care in clinical medicine and the monitor of ADR should be enhanced in order to improve the level of the reasonable medicine use.