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阿尔茨海默病药物治疗新进展 被引量：3

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摘要 本文有意避开美国食品药品管理局批准的治疗阿尔茨海默病(AD)的5种药物(他克林、多奈哌齐、利凡斯的明、加兰他敏和美金刚),从四抗(抗炎、抗氧化、抗胆固醇、抗β-淀粉样蛋白)、两拟(拟胆碱和拟谷氨酸)角度综述抗AD药的新进展。
作者 喻东山
机构地区 南京医科大学附属脑科医院
出处 《临床合理用药杂志》 2011年第07X期2-4,共3页 Chinese Journal of Clinical Rational Drug Use
关键词 阿尔茨海默病 药物疗法 进展
分类号 R749.16 [医药卫生—神经病学与精神病学]
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参考文献15

  • 1Kelley BJ,Petersen RC.Alzheimer′s disease and mild cognitive impairment[J].Neurol Clin,2007,25(3):577-609.
  • 2Mintzer JE.The search for better noncholinergic treatment options for alzheimer′s disease[J].J Clin Psychiatry,2003,64(Suppl 9):18-22.
  • 3Seow D,Gauthier S.Pharmacotherapy of alzheimer disease[J].Can J Psychiatry,2007,52(10):620-629.
  • 4Mazza M,Capuano A,Bria P,et al.Ginkgo biloba and donepezil:a comparison in the treatment of Alzheimer′s dementia in a randomized placebo-controlled double-blind study[J].Eur J Neurol,2006,13(9):981-985.
  • 5Tobinick E,Gross H,Weinberger A,et al.TNF-alpha modulation for treatment of Alzheimer′s disease:a 6-month pilot study[J].MedGenMed,2006,8(2):25.
  • 6Tobinick E.Perispinal etanercept for treatment of Alzheimer′s disease[J].Curr Alzheimer Res,2007,4(5):550-552.
  • 7Holmquist L,Stuchbury G,Berbaum K,et al.Lipoic acid as a novel treatment for Alzheimer′s disease and related dementias[J].Pharmacol Ther,2007,113(1):154-164.
  • 8Wei ZH,He QB,Wang H,et al.Meta-analysis:the efficacy of nootropic agent Cerebrolysin in the treatment of Alzheimer′s disease[J].J Neural Transm,2007,114(5):629-634.
  • 9Sparks DL,Connor DJ,Sabbagh MN,et al.Circulating cholesterol levels,apolipoprotein E genotype and dementia severity influence the benefit of atorvastatin treatment in Alzheimer′s disease:results of the Alzheimer′s disease cholesterol-lowering treatment(ADCLT) trial[J].Acta Neurol Scand,2006,114(Suppl 185):3-7.
  • 10Zhou B,Teramukai S,Fukushima M.Prevention and treatment of dementia or Alzheimer′s disease by statins:a meta-analysis[J].Dement Geriatr Cogn Disord,2007,23(3):194-201.

同被引文献67

  • 1曹雯炜,张丽,钟根龙,李焰生.美国痴呆最新药物治疗临床操作指南[J].中国卒中杂志,2008,3(6):423-429. 被引量：21
  • 2吴泰相,刘关键,李静.影响系统评价质量的主要因素浅析[J].中国循证医学杂志,2005,5(1):51-58. 被引量：50
  • 3Querfurth HW,LaFerla FM. Alzheimer's disease[J].New England Journal of Medicine,2010,(04):329-344.
  • 4Williams RJ,Spencer JP. Flavonoids,cognition,and dementia:actions,mechanisms,and potential therapeutic utility for Alzheimer disease[J].Free Radical Biology and Medicine,2012,(01):35-45.
  • 5Spencer JP. Beyond antioxidants:the cellular and molecular interactions of favonoids and how these underpin their actions on the brain[J].Proceedings of the Nutrition Society,2010,(02):244-260.
  • 6Hanrahan JR,Chebib M,Johnston GA. Flavonoid modulation of GABA(A)receptors[J].British Journal of Pharmacology,2011,(02):234-245.
  • 7Xi YD,Yu HL,Ding J. Flavonoids protect cerebrovascular endothelial cells through Nrf2 and PI3K from β-amyloid peptide-induced oxidative damage[J].Current Neurovascular Research,2012,(01):32-41.
  • 8Downward J. PI 3-kinase,Akt and cell survival.,Seminars in Cell[J].Seminars in Cell and Developmental Biology,2004,(02):177-182.doi:10.1016/j.semcdb.2004.01.002.
  • 9Zeng KW,Fu H,Liu GX. Icariin attenuates lipopolysacc haride-induced microglial activation and resultant death of neurons by inhibiting TAK1/IKK/NF-kappaB and JNK/p38 MAPK pathways[J].International Journal of Immunopharmacology,2010,(06):668-678.
  • 10Hayden MS,Ghosh S. Shared Principles in NF-κB Signaling[J].Cell,2008,(03):344-362.

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临床合理用药杂志
2011年 第07X期

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