摘要
目的观察活血化瘀、软坚散结药配伍治疗肝纤维化时对肝功能的影响。方法采用自制方剂化肝汤1号(醋鳖甲、黄芩、柴胡、赤芍等)治疗肝纤维化60例。结果丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、谷氨酸转移酶(GGT)、AST/ALT治疗组治疗前为(61.77±10.36)U/L、(134.53±23.09)U/L、(123.23±17.31)U/L、(2.18±0.13),治疗后为(33.33±6.50)U/L、(56.27±10.92)U/L、(60.20±7.40)U/L、(1.71±0.27)。对照组治疗前为(59.03±7.90)U/L、(123.30±14.21)U/L、(120.60±13.84)U/L、(2.09±0.07),治疗后为(42.70±6.52)U/L、(84.67±11.82)U/L、(81.63±10.17)U/L、(1.99±0.16),治疗组和对照组治疗前后比较差异均有统计学意义(P<0.05),治疗组与对照组治疗后比较差异均有统计学意义(P<0.05)。结论化肝汤1号可有效的降低肝细胞的损害程度,促进受损细胞修复,从而改善肝功能。
Objective To observe the blood circulation,endometriosis drug compatibility of the treatment of liver fibrosis on liver function.Methods Using self-prescription of liver soup 1（vinegar turtle,skullcap,bupleurum root,red peony,etc.） in the treatment of liver fibrosis in 60 cases.Results ALT,AST,GGT,AST / ALT before treatment to（61.77±10.36）U/L、（134.53±23.09）U/L、（123.23±17.31）U/L、（2.18±0.13）,after treatment（33.33±6.50）U/L、（56.27±10.92）U/L、（60.20±7.40）U/L、（1.71±0.27）.Control group before treatment（59.03±7.90）U/L、（123.30±14.21）U/L、（120.60±13.84）U/L、（2.09±0.07）,after treatment（42.70±6.52）U/L、（84.67±11.82）U/L、（81.63±10.17）U/L、（1.99±0.16）,treatment and control groups before and after treatment were significantly differences（P0.05）,treatment group and control group after treatment（P0.05）,there are significant differences.Conclusion The liver soup 1 can effectively reduce the degree of liver cell damage and promote repair of damaged cells,thus improving liver function.
出处
《临床合理用药杂志》
2011年第07X期21-22,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
肝纤维化
肝功能
化肝汤1号
Liver fibrosis
Liver function
Liver soup 1
