解语丹加减治疗脑卒中后肢体麻木疗效观察

Clinical Curative Effect Observation of Jie-yu-dan on Limbs Numbness after Stroke

目的：观察解语丹治疗脑卒中后肢体麻木的临床疗效。方法：将70例入选病例随机分为治疗组35例和对照组35例。对照组予以常规对症处理,治疗组在常规对症处理基础上予以汤剂解语丹加减内服,两组均治疗3周,观察治疗前后肢体麻木疗效。结果：治疗组治愈20例,有效12例,无效3例,总有效率为91.43%（95%C I=76.74%~98.18%）;对照组治愈12例,有效13例,无效10例,总有效率为71.43%（95%C I=56.46%~86.40%）;两组综合疗效比较（u=2.136 0,P=0.032 9）,差异有显著性意义;且未发现明显毒副反应。结论：解语丹配合常规对症处理治疗卒中后肢体麻木的疗效优于常规对症处理,且安全副作用少,其收益为OR=0.23（95%C I=0.06~0.95）,NNT=5（95%C I=2.6~56.2）。

Objective： To observe the clinical effect of Jie-yu-dan on limbs numbness atter stroke, Memous： 70 selected cases were randomly divided into treatment group of 35 patients and control-group of 35 patients. The cases in control group were treated with routine symptomatic treatment, and the ones in treatment group were treated with Jie-yu-dan on the basis of above treatment. One course of treatment included three weeks. At last the curative effects were observed. Results： In treatment group 20 cases were recovered, 12 ones effective, 3 ones ineffective. The total effective rate was 91.43%, （95% CI =76.74% -98.18% ）. In control group 12 cases were re covered, 13 ones effective, and 10 ones ineffective. The total effective rate was 71.43%, （95% CI = 56. 46% - 86. 40% ）. There was significant difference between the two groups（u =2. 136 0,P =0. 032 9）. Conclusion： fie- yu-dan combined with routine symptomatic treatment has better effect on limbs numbness after stroke than only routine symptomatic treatment, and fewer side effect and safe, OR = 0. 23 （ 95 % CI = 0. 06 - 0. 95 ）, NNT = 5 （95% CI =2. 6 -56. 2）.