干扰素治疗慢性乙型肝炎患者的观察与护理

Observation and Nursing Care of Interferon Treatment for Chronic Hepatitis B Patients

目的观察干扰素治疗慢性乙型肝炎患者的临床疗效,探讨系统的护理干预对疾病转归的影响。方法对2007年2月～2008年12月我院收治的慢性乙型肝炎患者65例给予α-干扰素治疗,500万IU/次,3次/周,4周为一个疗程,连续治疗6个疗程。在治疗期间进行系统的护理干预,观察患者的预后。结果在系统的护理干预下,患者对慢性乙型肝炎及干扰素的相关知识均有不同程度的了解;采用α-干扰素治疗期间,51例患者能做到定期监测,监测率78.46%;25例患者血清HBeAg转阴,转阴率为38.46%。结论系统的护理干预可提高干扰素治疗慢性乙型肝炎患者的用药、监测依从性,减少并发症,保障用药安全有效。

Objective To observe the clinical efficacy of interferon treatment of chronic hepatitis B patients,to explore the effect of systematic nursing intervention on the prognosis of the disease.Methods From February 2007 to December 2008 in our hospital 65 patients with chronic hepatitis B were given α-interferon therapy,5 million IU /per time,3 times a week,4 weeks for a treatment course,continuous treatment for 6 cycles.To take systematic nursing intervention dursing treatment and to observe the patients＇ prognosis.Results Under the systematic nursing intervention,the patients had the understanding of different levels in chronic hepatitis B and interferon-related knowledge;dursing the period of the use of α-interferon treatment,51 patients were able to do regular monitoring,monitoring rate was 78.46%;serum HBeAg of 25 patients was negative,the negative rate was 38.46%.Conclusion Systematic nursing intervention can improve the treatment of chronic hepatitis B patients with interferon medication,monitoring compliance,reduce complications,ensure safe and effective drugs.