老年糖耐量正常者糖尿病危险因素综合干预后的变化

The change of elderly persons with normal glucose tolerance after the comprehensive intervention of diabetes risk factors

目的通过综合干预老年糖耐量正常(NGT)者糖尿病危险因素,探索综合干预对患者血压、血脂、体质指数(BMI)的影响。方法调查112名老年NGT者的糖尿病危险因素,综合干预其中57名NGT者的血压、血脂、体质指数(BMI)和生活方式等,并定期随访3年。结果综合干预后,TC≥5.23 mmol/L、LDL-C≥3.15 mmol/L、TG≥1.7 mmol/L分别减少40.35%、26.32%、10.52%,肥胖者(BMI≥30)减少15.78%,收缩压由(128.17±12.87)mmHg下降为(124.04±11.26)mmHg,舒张压由(75.19±7.28)mmHg下降为(70.03±6.84)mmHg。结论综合干预可显著降低患者高血压、高血脂和BMI水平,对预防或延缓老年NGT者进展为糖调节异常(IGR)具有一定的作用效果。

Objective To analyze its influence on blood pressure,blood lipid and body mass index through comprehensively intervening on normal glucose tolerance（NGT） in the elderly.Methods The baseline survey for DM factors was carried out in 112 NGT.Comprehensive interventions on hypertension,dyslipidemia,body mass index and lifestyle of 57 NGT were conducted and followed up 3 years.Results The rates of TC≥5.23 mmol/L,LDL≥3.15 mmol/L,TG≥1.7 mmol/L and BMI≥30 kg/m2 reduced by 40.35%,26.32%,10.52% and 15.78%（P0.05） respectively.Systolic blood pressure decreased from（128.17±12.87） mmHg to（124.04±11.26） mmHg（P0.01）.Diastolic blood pressure decreased from（75.19±7.28） mmHg to（70.03±6.84） mmHg（P0.01）.Conclusion The levels of blood pressure,TC,LDL,TG and BMI reduced significantly through comprehensive intervention,which can prevent or delay the occurrence of DM or IGR.